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Catalog Number:
40129
CAS Number:
220210-56-0
3-(tert-Butoxycarbonyl)phenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
3-(tert-Butoxycarbonyl)benzeneboronic acid
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Product Information

3-(tert-Butoxycarbonyl)phenylboronic acid is a versatile compound widely utilized in organic synthesis and medicinal chemistry. This boronic acid derivative is particularly valued for its ability to form stable complexes with diols, making it an essential reagent in the development of various pharmaceutical intermediates and agrochemicals. Its unique tert-butoxycarbonyl (Boc) protecting group enhances its stability and reactivity, allowing for selective reactions in complex synthetic pathways. Researchers often employ this compound in Suzuki-Miyaura cross-coupling reactions, which are pivotal in constructing carbon-carbon bonds, thereby facilitating the synthesis of complex organic molecules.

In addition to its synthetic applications, 3-(tert-Butoxycarbonyl)phenylboronic acid has shown potential in the development of targeted therapies and drug delivery systems. Its ability to interact with biological molecules opens avenues for innovative research in cancer treatment and other therapeutic areas. The compound's favorable properties, such as solubility and reactivity, make it a preferred choice for researchers looking to streamline their synthesis processes while achieving high yields. With its broad applicability and significant advantages over similar compounds, this boronic acid derivative is an invaluable tool for professionals in the chemical and pharmaceutical industries.

Synonyms
3-(tert-Butoxycarbonyl)benzeneboronic acid
CAS Number
220210-56-0
Purity
97 - 105% (Assay by titration)
Molecular Formula
C11H15BO4
Molecular Weight
222.05
MDL Number
MFCD01630855
PubChem ID
2773299
Melting Point
102 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
3-(tert-Butoxycarbonyl)benzeneboronic acid
CAS Number
220210-56-0
Purity
97 - 105% (Assay by titration)
Molecular Formula
C11H15BO4
Molecular Weight
222.05
MDL Number
MFCD01630855
PubChem ID
2773299
Melting Point
102 °C (Lit.)
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

3-(tert-Butoxycarbonyl)phenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key intermediate in the synthesis of various organic molecules, particularly in the development of pharmaceuticals and agrochemicals.
  • Cross-Coupling Reactions: It is commonly used in Suzuki-Miyaura coupling reactions, allowing for the formation of carbon-carbon bonds, which is essential in creating complex organic structures.
  • Drug Development: Researchers leverage its properties to design and synthesize new drug candidates, particularly those targeting specific biological pathways.
  • Material Science: The compound is applied in the development of advanced materials, including polymers and nanomaterials, enhancing their properties for various applications.
  • Bioconjugation: It plays a role in bioconjugation strategies, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.

Citations