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Catalog Number:
40088
CAS Number:
17865-11-1
4-(Trimethylsilyl)phenylboronic acid
Purity:
95 - 105% (Assay by titration)
Synonym(s):
4-(Trimethylsilyl)benzeneboronic acid
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Product Information

4-(Trimethylsilyl)phenylboronic acid is a versatile organoboron compound widely utilized in organic synthesis and medicinal chemistry. This compound features a trimethylsilyl group that enhances its solubility and stability, making it an excellent choice for various applications, including Suzuki-Miyaura cross-coupling reactions. Its unique structure allows for the formation of carbon-carbon bonds, which is crucial in the development of complex organic molecules, pharmaceuticals, and agrochemicals. Researchers appreciate its ability to facilitate the synthesis of biologically active compounds, thereby accelerating drug discovery processes.

In addition to its synthetic applications, 4-(Trimethylsilyl)phenylboronic acid is also employed in the development of sensors and materials science. Its boronic acid functionality enables it to interact selectively with diols, making it useful in creating responsive materials and chemical sensors. This compound stands out due to its ease of use and effectiveness in various chemical transformations, providing significant advantages over other boronic acids in terms of reactivity and functional group tolerance.

Synonyms
4-(Trimethylsilyl)benzeneboronic acid
CAS Number
17865-11-1
Purity
95 - 105% (Assay by titration)
Molecular Formula
C9H15BO2Si
Molecular Weight
194.11
MDL Number
MFCD00093348
PubChem ID
1710
Melting Point
173 - 178 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-(Trimethylsilyl)benzeneboronic acid
CAS Number
17865-11-1
Purity
95 - 105% (Assay by titration)
Molecular Formula
C9H15BO2Si
Molecular Weight
194.11
MDL Number
MFCD00093348
PubChem ID
1710
Melting Point
173 - 178 °C
Appearance
White to off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-(Trimethylsilyl)phenylboronic acid is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a key reagent in the Suzuki-Miyaura cross-coupling reaction, allowing chemists to create complex organic molecules efficiently.
  • Pharmaceutical Development: It plays a crucial role in the synthesis of pharmaceutical intermediates, aiding in the development of new drugs with enhanced efficacy and reduced side effects.
  • Material Science: The compound is used in the modification of polymers and materials, improving their properties for applications in electronics and coatings.
  • Analytical Chemistry: It is employed in the development of sensors and analytical methods, providing high sensitivity and selectivity in detecting various analytes.
  • Environmental Chemistry: This chemical is used in studies related to pollutant degradation and environmental monitoring, helping researchers understand and mitigate environmental impacts.

Citations