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Catalog Number:
39706
CAS Number:
756526-03-1
Bis(NHS)PEG5
Purity:
≥ 90%
Synonym(s):
Di(N-succinimidyl) 4,7,10,13,16-pentaoxanonadecanedioate, 4,7,10,13,16-Pentaoxanonadecanedioic acid di(N-succinimidyl)ester
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$80.62 /25MG
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Product Information

Bis(NHS)PEG5 is a versatile compound widely utilized in bioconjugation and drug delivery applications. This polyethylene glycol (PEG) derivative features a unique structure that enhances solubility and biocompatibility, making it an ideal choice for researchers and industry professionals working in the fields of pharmaceuticals and biotechnology. Its NHS (N-hydroxysuccinimide) groups facilitate efficient coupling with amine-containing biomolecules, allowing for the creation of stable conjugates that can be used in targeted therapies, diagnostics, and imaging applications.

The compound's ability to improve the pharmacokinetics of therapeutic agents while minimizing immunogenicity is a notable advantage, making it particularly valuable in the development of antibody-drug conjugates and other biopharmaceuticals. Additionally, Bis(NHS)PEG5 can be employed in the synthesis of functionalized surfaces for biosensors and drug delivery systems, providing a platform for innovative therapeutic solutions. Its unique properties and practical applications position it as a key reagent for advancing research and development in the life sciences.

Synonyms
Di(N-succinimidyl) 4,7,10,13,16-pentaoxanonadecanedioate, 4,7,10,13,16-Pentaoxanonadecanedioic acid di(N-succinimidyl)ester
CAS Number
756526-03-1
Purity
≥ 90%
Molecular Formula
C22H32N2O13
Molecular Weight
532.5
MDL Number
MFCD11041118
PubChem ID
51340935
Appearance
Colorless gel
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Di(N-succinimidyl) 4,7,10,13,16-pentaoxanonadecanedioate, 4,7,10,13,16-Pentaoxanonadecanedioic acid di(N-succinimidyl)ester
CAS Number
756526-03-1
Purity
≥ 90%
Molecular Formula
C22H32N2O13
Molecular Weight
532.5
MDL Number
MFCD11041118
PubChem ID
51340935
Appearance
Colorless gel
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Bis(NHS)PEG5 is widely utilized in research focused on:

  • Bioconjugation: This compound serves as an effective linker for attaching biomolecules, such as proteins or antibodies, to surfaces or other molecules. This application is crucial in the development of targeted drug delivery systems.
  • Drug Development: In pharmaceutical research, it enhances the solubility and stability of drug candidates, improving their bioavailability. This is particularly beneficial in formulating therapies for poorly soluble drugs.
  • Diagnostics: It is used in the creation of diagnostic agents, allowing for improved imaging and detection of diseases. This application is vital in the field of medical imaging and biomarker discovery.
  • Polymer Chemistry: The compound is employed in synthesizing advanced polymers with tailored properties, which can be used in various industrial applications, including coatings and adhesives.
  • Research Reagents: It acts as a versatile reagent in biochemical assays, facilitating the study of protein interactions and cellular processes, which is essential for advancing biological research.

Citations