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Catalog Number:
39668
CAS Number:
25021-08-3
2-Maleimidoacetic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid
Documents
$94.54 /50MG
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Product Information

2-Maleimidoacetic acid is a versatile compound widely utilized in bioconjugation and polymer chemistry due to its unique reactivity and functional properties. This compound features a maleimide group that allows for selective and efficient coupling with thiol-containing molecules, making it an excellent choice for developing targeted drug delivery systems and creating stable bioconjugates. Its ability to form covalent bonds with proteins and peptides enhances its application in the fields of biotechnology and pharmaceuticals, particularly in the design of antibody-drug conjugates and diagnostic assays.

In addition to its applications in bioconjugation, 2-Maleimidoacetic acid is also employed in the synthesis of functionalized polymers and materials. Researchers appreciate its stability and ease of use, which facilitate the development of advanced materials with tailored properties for various applications, including sensors and drug delivery vehicles. With its robust performance and adaptability, 2-Maleimidoacetic acid stands out as a valuable tool for professionals seeking innovative solutions in chemical research and development.

Synonyms
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid
CAS Number
25021-08-3
Purity
≥ 98% (HPLC)
Molecular Formula
C6H5NO4
Molecular Weight
155.11
MDL Number
MFCD00457254
PubChem ID
319935
Melting Point
114 - 118 °C
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid
CAS Number
25021-08-3
Purity
≥ 98% (HPLC)
Molecular Formula
C6H5NO4
Molecular Weight
155.11
MDL Number
MFCD00457254
PubChem ID
319935
Melting Point
114 - 118 °C
Appearance
White to off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Maleimidoacetic acid is widely utilized in research focused on:

  • Bioconjugation: This compound is commonly used to link biomolecules, such as proteins and peptides, to other molecules for drug delivery systems, enhancing the efficacy of therapeutic agents.
  • Diagnostic Applications: It plays a crucial role in the development of diagnostic tools, particularly in the creation of biosensors that detect specific biomolecules, aiding in early disease detection.
  • Polymer Chemistry: In the field of polymer science, it is employed to modify polymer surfaces, improving their properties for applications in coatings and adhesives.
  • Drug Development: Researchers utilize it in the synthesis of novel pharmaceuticals, particularly in creating compounds with improved bioavailability and targeted delivery mechanisms.
  • Research in Cancer Therapy: It is being explored for its potential in targeted cancer therapies, allowing for the selective delivery of cytotoxic agents to cancer cells, minimizing damage to healthy tissues.

Citations