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Catalog Number:
39650
CAS Number:
108149-60-6
(S)-(-)-3-tert-Butoxycarbonyl-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine
Purity:
≥ 98.5% (Chiral purity)
Synonym(s):
(S)-(-)-3-Boc-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine, Methyl (S)-(-)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-oxazolidinecarboxylate
Hazmat
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Product Information

(S)-(-)-3-tert-Butoxycarbonyl-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine is a versatile compound widely utilized in the synthesis of various pharmaceuticals and agrochemicals. This compound features a unique oxazolidine structure that enhances its stability and reactivity, making it an excellent choice for researchers and industry professionals involved in organic synthesis. Its ability to act as a chiral building block allows for the development of enantiomerically pure compounds, which is crucial in the pharmaceutical industry for creating effective and safe medications.

In addition to its applications in drug development, this compound is also valuable in the production of fine chemicals and intermediates. Its distinctive properties enable it to facilitate complex reactions, thus streamlining the synthesis process and improving yields. Researchers have found it particularly useful in asymmetric synthesis, where the need for chirality is paramount. With its robust profile, (S)-(-)-3-tert-Butoxycarbonyl-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine stands out as a key ingredient in advancing chemical research and industrial applications.

Synonyms
(S)-(-)-3-Boc-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine, Methyl (S)-(-)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-oxazolidinecarboxylate
CAS Number
108149-60-6
Purity
≥ 98.5% (Chiral purity)
Molecular Formula
C12H21NO5
Molecular Weight
259.3
MDL Number
MFCD00192279
PubChem ID
5138497
Density
1.08 g/mL at 25 ?C
Appearance
Colorless to slightly yellow liquid
Boiling Point
101 - 102 ?C / 2 mmHg (Lit.)
Refractive Index
n20D 1.44
Optical Rotation
[α]20D = −55 +/- 2 ° (C = 1.3 in Chloroform)
Conditions
Store at RT
General Information
Synonyms
(S)-(-)-3-Boc-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine, Methyl (S)-(-)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-oxazolidinecarboxylate
CAS Number
108149-60-6
Purity
≥ 98.5% (Chiral purity)
Molecular Formula
C12H21NO5
Molecular Weight
259.3
MDL Number
MFCD00192279
PubChem ID
5138497
Density
1.08 g/mL at 25 ?C
Appearance
Colorless to slightly yellow liquid
Boiling Point
101 - 102 ?C / 2 mmHg (Lit.)
Refractive Index
n20D 1.44
Optical Rotation
[α]20D = −55 +/- 2 ° (C = 1.3 in Chloroform)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-(-)-3-tert-Butoxycarbonyl-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs that target neurological disorders.
  • Peptide Synthesis: It is used in the solid-phase synthesis of peptides, enhancing the efficiency and yield of the process, which is crucial for producing therapeutic proteins.
  • Chiral Auxiliary: The compound acts as a chiral auxiliary in asymmetric synthesis, allowing chemists to produce enantiomerically pure compounds, which are vital in drug formulation.
  • Research in Organic Chemistry: It provides a versatile framework for the exploration of new synthetic pathways and methodologies, aiding researchers in discovering novel compounds.
  • Bioconjugation Techniques: This chemical is employed in bioconjugation strategies, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutics.

Citations