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Catalog Number:
39636
CAS Number:
34281-92-0
(1S,2R)-(+)-trans-2-Phenyl-1-cyclohexanol
Purity:
≥ 97.5% (Chiral purity)
Synonym(s):
(1S,2R)-2-Phenyl-1-cyclohexanol, (1S-trans)-2-Phenylcyclohexanol
Documents
$134.70 /100MG
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Product Information

(1S,2R)-(+)-trans-2-Phenyl-1-cyclohexanol is a versatile compound widely recognized for its applications in organic synthesis and pharmaceutical development. This chiral alcohol serves as a valuable intermediate in the synthesis of various pharmaceuticals, particularly in the production of chiral drugs where stereochemistry plays a crucial role in efficacy and safety. Its unique structure allows for the development of compounds with specific biological activities, making it an essential building block in medicinal chemistry.

In addition to its pharmaceutical applications, (1S,2R)-(+)-trans-2-Phenyl-1-cyclohexanol is utilized in the production of fragrances and flavoring agents, contributing to the formulation of high-quality consumer products. Researchers appreciate its stability and ease of manipulation in laboratory settings, which enhances its appeal for both academic and industrial applications. With its significant role in advancing drug discovery and formulation, this compound stands out as a key player in the chemical industry.

Synonyms
(1S,2R)-2-Phenyl-1-cyclohexanol, (1S-trans)-2-Phenylcyclohexanol
CAS Number
34281-92-0
Purity
≥ 97.5% (Chiral purity)
Molecular Formula
C12H16O
Molecular Weight
176.26
MDL Number
MFCD00066432
PubChem ID
15046
Melting Point
63 - 67 °C
Appearance
White to off white crystalline powder
Boiling Point
105 °C / 3 mmHg (Lit.)
Optical Rotation
[α]20D = 55 - 61 ° (C=1 in Methanol)
Conditions
Store at RT
General Information
Synonyms
(1S,2R)-2-Phenyl-1-cyclohexanol, (1S-trans)-2-Phenylcyclohexanol
CAS Number
34281-92-0
Purity
≥ 97.5% (Chiral purity)
Molecular Formula
C12H16O
Molecular Weight
176.26
MDL Number
MFCD00066432
PubChem ID
15046
Melting Point
63 - 67 °C
Appearance
White to off white crystalline powder
Boiling Point
105 °C / 3 mmHg (Lit.)
Optical Rotation
[α]20D = 55 - 61 ° (C=1 in Methanol)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(1S,2R)-(+)-trans-2-Phenyl-1-cyclohexanol is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting central nervous system disorders. Its unique stereochemistry can enhance the efficacy and selectivity of drug candidates.
  • Flavor and Fragrance Industry: Its pleasant aroma makes it valuable in the formulation of perfumes and flavoring agents, providing a natural scent profile that is often preferred over synthetic alternatives.
  • Chiral Catalysis: This compound is used in asymmetric synthesis, acting as a chiral ligand in catalytic reactions. This application is crucial for producing enantiomerically pure compounds, which are essential in many chemical processes.
  • Material Science: It can be incorporated into polymer formulations to enhance properties such as thermal stability and mechanical strength, making it beneficial for creating advanced materials in various industrial applications.
  • Research in Organic Chemistry: The compound is a valuable tool for studying reaction mechanisms and stereochemistry, providing insights that can lead to the development of new synthetic methodologies.

Citations