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Catalog Number:
39571
CAS Number:
365996-30-1
(1S,2R)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine
Purity:
≥ 99% (GC)
Synonym(s):
(1S,2R)-N1-Boc-1,2-cyclohexanediamine, (1S,2R)-2-Amino-1-(tert-butoxycarbonylamino)cyclohexane, (1S,2R)-2-Amino-1-(Boc-amino)cyclohexane
Documents
$70.50 /250MG
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Product Information

(1S,2R)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine is a versatile compound widely utilized in the synthesis of various pharmaceutical intermediates and agrochemicals. This compound, also known as tert-butyl N-[(1S,2R)-2-aminocyclohexyl]carbamate, features a unique bicyclic structure that enhances its reactivity and stability, making it an ideal candidate for applications in medicinal chemistry. Its ability to serve as a protecting group for amines allows researchers to streamline synthetic pathways, thereby improving yields and reducing the complexity of multi-step reactions.

In the pharmaceutical industry, this compound is particularly valuable in the development of chiral drugs, where its stereochemistry plays a crucial role in biological activity. Additionally, its use in the production of agrochemicals highlights its importance in enhancing crop protection formulations. With its favorable properties and practical applications, (1S,2R)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine stands out as a key building block for researchers and industry professionals seeking efficient and effective solutions in their chemical processes.

Synonyms
(1S,2R)-N1-Boc-1,2-cyclohexanediamine, (1S,2R)-2-Amino-1-(tert-butoxycarbonylamino)cyclohexane, (1S,2R)-2-Amino-1-(Boc-amino)cyclohexane
CAS Number
365996-30-1
Purity
≥ 99% (GC)
Molecular Formula
C11H22N2O2
Molecular Weight
214.31
MDL Number
MFCD09952105
PubChem ID
3268011
Appearance
Colorless to pale yellow liquid
Optical Rotation
[a]20D = -5 to -7 ° (C=1 in CH2Cl2)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(1S,2R)-N1-Boc-1,2-cyclohexanediamine, (1S,2R)-2-Amino-1-(tert-butoxycarbonylamino)cyclohexane, (1S,2R)-2-Amino-1-(Boc-amino)cyclohexane
CAS Number
365996-30-1
Purity
≥ 99% (GC)
Molecular Formula
C11H22N2O2
Molecular Weight
214.31
MDL Number
MFCD09952105
PubChem ID
3268011
Appearance
Colorless to pale yellow liquid
Optical Rotation
[a]20D = -5 to -7 ° (C=1 in CH2Cl2)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(1S,2R)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders due to its ability to cross the blood-brain barrier.
  • Peptide Synthesis: It is commonly used in peptide synthesis as a protecting group for amines, allowing for the selective modification of amino acids without affecting other functional groups, which is crucial in the production of complex peptides.
  • Material Science: The compound finds applications in the development of polymeric materials, enhancing properties such as flexibility and thermal stability, making it valuable in industries like automotive and aerospace.
  • Bioconjugation: Its reactive functional groups enable bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in drug delivery systems and diagnostic applications.
  • Research in Organic Chemistry: This chemical is a useful reagent in organic synthesis, allowing researchers to explore new reaction pathways and mechanisms, thus contributing to advancements in synthetic methodologies.

Citations