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Catalog Number:
39570
CAS Number:
146504-07-6
(1R,2R)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine
Purity:
≥ 98% (Assay by titration, GC)
Synonym(s):
(1R,2R)-N1-Boc-1,2-cyclohexanediamine, (1R,2R)-2-Amino-1-(tert-butoxycarbonylamino)cyclohexane, (1R,2R)-2-Amino-1-(Boc-amino)cyclohexane, tert-Butyl [(1R,2R)-2-aminocyclohexyl]carbamate
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Product Information

(1R,2R)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine is a versatile compound widely utilized in the synthesis of pharmaceuticals and agrochemicals. This compound, also known as tert-butyl N-[(1R,2R)-2-aminocyclohexyl]carbamate, features a unique structure that enhances its reactivity and stability, making it an excellent choice for researchers and industry professionals. Its ability to serve as a protecting group for amines allows for selective reactions, which is crucial in complex organic synthesis.

In the pharmaceutical industry, this compound is particularly valuable in the development of chiral drugs, where its stereochemistry plays a significant role in the efficacy and safety of the final product. Additionally, its applications extend to the production of agrochemicals, where it can be used to improve the bioavailability of active ingredients. The compound's favorable properties, such as its solubility and stability, make it an ideal candidate for various formulations, ensuring optimal performance in both research and practical applications.

Synonyms
(1R,2R)-N1-Boc-1,2-cyclohexanediamine, (1R,2R)-2-Amino-1-(tert-butoxycarbonylamino)cyclohexane, (1R,2R)-2-Amino-1-(Boc-amino)cyclohexane, tert-Butyl [(1R,2R)-2-aminocyclohexyl]carbamate
CAS Number
146504-07-6
Purity
≥ 98% (Assay by titration, GC)
Molecular Formula
C11H22N2O2
Molecular Weight
214.31
MDL Number
MFCD08726023
PubChem ID
3268011
Melting Point
114 - 118 °C
Appearance
White or off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(1R,2R)-N1-Boc-1,2-cyclohexanediamine, (1R,2R)-2-Amino-1-(tert-butoxycarbonylamino)cyclohexane, (1R,2R)-2-Amino-1-(Boc-amino)cyclohexane, tert-Butyl [(1R,2R)-2-aminocyclohexyl]carbamate
CAS Number
146504-07-6
Purity
≥ 98% (Assay by titration, GC)
Molecular Formula
C11H22N2O2
Molecular Weight
214.31
MDL Number
MFCD08726023
PubChem ID
3268011
Melting Point
114 - 118 °C
Appearance
White or off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(1R,2R)-N1-(tert-Butoxycarbonyl)-1,2-cyclohexanediamine is widely utilized in research focused on

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Peptide Synthesis: It is employed in solid-phase peptide synthesis, providing a protective group that enhances the stability and yield of peptide chains.
  • Bioconjugation: The compound is used in bioconjugation applications, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in drug delivery systems.
  • Analytical Chemistry: It acts as a derivatizing agent in analytical chemistry, improving the detection and quantification of amines in complex mixtures.
  • Material Science: This chemical finds applications in the development of polymers and materials, contributing to the creation of more durable and functional products.

Citations