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Catalog Number:
39566
CAS Number:
145080-95-1
Diethyl (S)-(-)-2-isocyanatoglutarate
Purity:
≥ 97% (GC)
Synonym(s):
Diethyl (S)-(-)-2-Isocyanatopentanedioate, (S)-(-)-2-Isocyanatoglutaric acid diethyl ester
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Product Information

Diethyl (S)-(-)-2-isocyanatoglutarate is a versatile compound known for its unique isocyanate functionality, making it a valuable intermediate in organic synthesis. This compound is particularly significant in the pharmaceutical and agrochemical industries, where it serves as a building block for the synthesis of various bioactive molecules. Its ability to react with nucleophiles allows for the formation of diverse derivatives, which can be tailored for specific applications, including drug development and the creation of agrochemicals. Researchers appreciate its efficiency in facilitating reactions that lead to complex structures, enhancing the potential for innovative solutions in medicinal chemistry and crop protection.

In addition to its synthetic utility, Diethyl (S)-(-)-2-isocyanatoglutarate exhibits favorable properties that contribute to its effectiveness. Its relatively low toxicity and high reactivity make it an attractive choice for chemists looking to streamline their processes while ensuring safety. This compound stands out among similar isocyanates due to its specific stereochemistry, which can influence the biological activity of the resulting products. As such, it holds promise for researchers aiming to develop new therapeutic agents or agricultural products with enhanced efficacy.

Synonyms
Diethyl (S)-(-)-2-Isocyanatopentanedioate, (S)-(-)-2-Isocyanatoglutaric acid diethyl ester
CAS Number
145080-95-1
Purity
≥ 97% (GC)
Molecular Formula
C10H15NO5
Molecular Weight
229.23
MDL Number
MFCD00191663
PubChem ID
350663
Density
1.13 g/mL
Appearance
White, yellow or green clear liquid
Boiling Point
151 °C / 10 mmHg
Refractive Index
n20D = 1.44
Optical Rotation
[α]20D = -41 to -46 ° (neat)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Diethyl (S)-(-)-2-Isocyanatopentanedioate, (S)-(-)-2-Isocyanatoglutaric acid diethyl ester
CAS Number
145080-95-1
Purity
≥ 97% (GC)
Molecular Formula
C10H15NO5
Molecular Weight
229.23
MDL Number
MFCD00191663
PubChem ID
350663
Density
1.13 g/mL
Appearance
White, yellow or green clear liquid
Boiling Point
151 °C / 10 mmHg
Refractive Index
n20D = 1.44
Optical Rotation
[α]20D = -41 to -46 ° (neat)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Diethyl (S)-(-)-2-isocyanatoglutarate is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting metabolic disorders.
  • Bioconjugation: It is used in bioconjugation processes to create stable linkages between biomolecules, enhancing drug delivery systems and targeted therapies.
  • Polymer Chemistry: The compound is employed in the production of specialty polymers, providing unique properties such as increased flexibility and improved thermal stability.
  • Analytical Chemistry: Researchers utilize it as a reagent for the derivatization of amino acids and other compounds, aiding in the accurate analysis and quantification of these substances.
  • Environmental Science: It is applied in studies related to the degradation of pollutants, helping to develop methods for environmental remediation.

Citations