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Catalog Number:
39249
CAS Number:
20554-84-1
Parthenolide
Purity:
≥ 99% (HPLC)
Synonym(s):
4,5a-Epoxy-6b-hydroxygermacra-1(10),11(13)-dien-12-oic acidg-lactone
Documents
$18.53 /25MG
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Product Information

Parthenolide is a naturally occurring sesquiterpene lactone primarily extracted from the plant *Tanacetum parthenium*, commonly known as feverfew. This compound has garnered significant attention in the fields of pharmacology and natural product chemistry due to its diverse biological activities, including anti-inflammatory, anti-cancer, and neuroprotective properties. Researchers have explored its potential in treating conditions such as migraines, arthritis, and various cancers, making it a valuable candidate for therapeutic applications.

In addition to its medicinal uses, Parthenolide serves as a potent bioactive agent in the development of functional foods and dietary supplements. Its unique ability to modulate inflammatory pathways and inhibit tumor growth positions it as a promising ingredient in health products aimed at enhancing wellness and preventing chronic diseases. With ongoing studies highlighting its efficacy and safety, Parthenolide continues to be a focal point for innovation in both pharmaceutical and nutraceutical industries.

Synonyms
4,5a-Epoxy-6b-hydroxygermacra-1(10),11(13)-dien-12-oic acidg-lactone
CAS Number
20554-84-1
Purity
≥ 99% (HPLC)
Molecular Formula
C15H20O3
Molecular Weight
248.32
MDL Number
MFCD00134592
PubChem ID
4692
Melting Point
114 - 116 °C
Appearance
Off-white powder
Optical Rotation
[α]20D = -81 to -86 ° (C = 1 in CHCl3)
Conditions
Store at 0 - 10 °C
General Information
Synonyms
4,5a-Epoxy-6b-hydroxygermacra-1(10),11(13)-dien-12-oic acidg-lactone
CAS Number
20554-84-1
Purity
≥ 99% (HPLC)
Molecular Formula
C15H20O3
Molecular Weight
248.32
MDL Number
MFCD00134592
PubChem ID
4692
Melting Point
114 - 116 °C
Appearance
Off-white powder
Optical Rotation
[α]20D = -81 to -86 ° (C = 1 in CHCl3)
Conditions
Store at 0 - 10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Parthenolide is widely utilized in research focused on:

  • Anti-inflammatory Applications: This compound is known for its ability to inhibit inflammatory pathways, making it valuable in developing treatments for conditions like arthritis and other inflammatory diseases.
  • Cancer Research: Parthenolide has shown promise in inducing apoptosis (programmed cell death) in various cancer cell lines, which is crucial for researchers looking for new cancer therapies.
  • Neuroprotective Effects: Studies suggest that it may protect neurons from damage, offering potential applications in treating neurodegenerative diseases such as Alzheimer's and Parkinson's.
  • Natural Pesticide Development: Its natural origin and effectiveness against certain pests make it a candidate for developing eco-friendly pesticides, appealing to the agricultural sector.
  • Antimicrobial Properties: Parthenolide has demonstrated activity against various pathogens, which can be beneficial in formulating new antimicrobial agents for medical and industrial use.

Citations