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Catalog Number:
38918
CAS Number:
105-45-3
Methyl acetoacetate
Purity:
≥ 99%
Synonym(s):
Acetoacetic acid methyl ester, Methyl 3-oxobutyrate
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$20.00 /25G
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Product Information

Methyl acetoacetate is a versatile compound widely utilized in the synthesis of various organic compounds, making it an essential building block in the chemical industry. This colorless liquid, with a fruity odor, is known for its reactivity and ability to participate in a range of chemical reactions, including Claisen condensation and Michael addition. Its unique properties allow it to serve as a precursor for the production of pharmaceuticals, agrochemicals, and flavoring agents. Researchers and industry professionals appreciate its role in synthesizing complex molecules, such as diketones and β-keto esters, which are pivotal in drug development and agricultural formulations.

In addition to its applications in organic synthesis, methyl acetoacetate is also employed in the production of dyes and pigments, enhancing the color properties of various materials. Its solubility in organic solvents makes it an ideal candidate for use in coatings and adhesives, providing improved performance characteristics. The compound's ability to act as a versatile intermediate positions it as a valuable resource for those looking to innovate in chemical synthesis and product formulation.

Synonyms
Acetoacetic acid methyl ester, Methyl 3-oxobutyrate
CAS Number
105-45-3
Purity
≥ 99%
Molecular Formula
C5H8O3
Molecular Weight
116.12
MDL Number
MFCD00008784
PubChem ID
7757
Melting Point
-81 to -79 °C
Density
1.080 at 25 °C
Appearance
Colorless clear liquid
Boiling Point
169 - 171 °C (Lit.)
Refractive Index
n20/D 1.420
Conditions
Store at RT
General Information
Synonyms
Acetoacetic acid methyl ester, Methyl 3-oxobutyrate
CAS Number
105-45-3
Purity
≥ 99%
Molecular Formula
C5H8O3
Molecular Weight
116.12
MDL Number
MFCD00008784
PubChem ID
7757
Melting Point
-81 to -79 °C
Density
1.080 at 25 °C
Appearance
Colorless clear liquid
Boiling Point
169 - 171 °C (Lit.)
Refractive Index
n20/D 1.420
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methyl acetoacetate is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a key intermediate in the synthesis of various drugs, including anti-inflammatory and analgesic medications, enhancing the efficiency of pharmaceutical development.
  • Flavor and Fragrance Industry: Methyl acetoacetate is used to create fruity flavors and fragrances, making it popular in food and cosmetic products. Its pleasant aroma adds value to consumer goods.
  • Polymer Production: It plays a significant role in the production of polymers and resins, contributing to the manufacturing of coatings and adhesives that are durable and resistant to environmental factors.
  • Organic Synthesis: Researchers utilize this compound in various organic synthesis reactions, including Michael additions and Claisen condensations, allowing for the creation of complex molecules in a straightforward manner.
  • Biochemical Research: Methyl acetoacetate is employed in biochemical studies to investigate metabolic pathways, particularly in studies related to ketone bodies and energy metabolism, providing insights into cellular processes.

Citations