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Catalog Number:
38720
CAS Number:
84371-65-3
Mifepristone
Purity:
≥ 98% (Assay by titration , HPLC)
Synonym(s):
11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
Documents
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Product Information

Mifepristone is a synthetic steroid with significant applications in reproductive health, primarily recognized for its role as an effective anti-progestin. This compound is widely used in medical settings for the termination of early pregnancies and the management of conditions such as Cushing's syndrome. Its mechanism of action involves blocking the effects of progesterone, a hormone essential for maintaining pregnancy, thereby facilitating the process of abortion in a safe and controlled manner.

In addition to its use in reproductive health, Mifepristone has shown promise in the treatment of certain types of cancer, particularly in hormone-sensitive tumors. Researchers are exploring its potential in combination therapies, enhancing the efficacy of existing cancer treatments. Mifepristone's unique properties, including its ability to selectively target progesterone receptors, make it a valuable tool in both clinical and research settings. Its versatility and effectiveness position it as a crucial compound for healthcare professionals and researchers focused on reproductive health and oncology.

Synonyms
11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
CAS Number
84371-65-3
Purity
≥ 98% (Assay by titration , HPLC)
Molecular Formula
C29H35NO2
Molecular Weight
429.6
MDL Number
MFCD00867226
PubChem ID
4196
Melting Point
192 - 198 °C
Appearance
White to light yellow crystalline powder
Optical Rotation
[α]20D = 138 - 144 ° (C = 0.5 in CHCl3)
Conditions
Store at 0 - 10 °C
General Information
Synonyms
11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
CAS Number
84371-65-3
Purity
≥ 98% (Assay by titration , HPLC)
Molecular Formula
C29H35NO2
Molecular Weight
429.6
MDL Number
MFCD00867226
PubChem ID
4196
Melting Point
192 - 198 °C
Appearance
White to light yellow crystalline powder
Optical Rotation
[α]20D = 138 - 144 ° (C = 0.5 in CHCl3)
Conditions
Store at 0 - 10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mifepristone is widely utilized in research focused on:

  • Medical Abortion: Mifepristone is primarily known for its role in medical abortion, where it is used in combination with another medication to terminate early pregnancies safely and effectively.
  • Hormonal Treatments: It is employed in the treatment of conditions like Cushing's syndrome, as it blocks the effects of cortisol, helping to manage symptoms and improve quality of life for patients.
  • Endometriosis Management: Mifepristone has shown promise in alleviating symptoms of endometriosis, providing relief from pain and discomfort associated with this condition.
  • Research in Reproductive Health: Researchers utilize Mifepristone to study its effects on reproductive health, including its potential in contraceptive development and understanding hormonal pathways.
  • Oncology Research: Emerging studies are exploring Mifepristone's potential in cancer treatment, particularly in hormone-sensitive tumors, offering a new avenue for therapeutic intervention.

Citations