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Catalog Number:
38498
CAS Number:
185332-92-7
Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt
Purity:
≥ 90% (Assay)
Synonym(s):
Sulfo-GMBS sodium salt
Documents
$95.24 /5MG
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Product Information

Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt is a versatile crosslinking reagent widely utilized in bioconjugation and protein labeling applications. This compound features a sulfonate group that enhances its solubility in aqueous solutions, making it particularly advantageous for use in biological systems. Its unique structure allows for selective conjugation to thiol-containing biomolecules, facilitating the development of targeted drug delivery systems and diagnostic tools. Researchers in the fields of biochemistry and molecular biology often leverage this compound to create stable conjugates for various applications, including antibody-drug conjugates and fluorescent labeling of proteins.

The sodium salt form of this compound offers improved stability and ease of handling, making it an ideal choice for laboratory settings. Its ability to form covalent bonds with proteins and peptides under mild conditions allows for the preservation of biological activity, which is crucial in therapeutic and diagnostic applications. With its reliable performance and compatibility with a range of biomolecules, Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt stands out as a key reagent for researchers aiming to innovate in the fields of drug development and molecular imaging.

Synonyms
Sulfo-GMBS sodium salt
CAS Number
185332-92-7
Purity
≥ 90% (Assay)
Molecular Formula
C12H11N2NaO9S
Molecular Weight
382.28
MDL Number
MFCD17215919
PubChem ID
23683309
Appearance
White powder
Conditions
Store at < -10 °C
General Information
Synonyms
Sulfo-GMBS sodium salt
CAS Number
185332-92-7
Purity
≥ 90% (Assay)
Molecular Formula
C12H11N2NaO9S
Molecular Weight
382.28
MDL Number
MFCD17215919
PubChem ID
23683309
Appearance
White powder
Conditions
Store at < -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Sulfo-N-succinimidyl 4-maleimidobutyrate sodium salt is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking proteins, antibodies, or other biomolecules to surfaces or each other, enhancing the specificity and efficacy of drug delivery systems.
  • Diagnostic Applications: It is used in the development of diagnostic kits, particularly in assays where precise binding of biomolecules is crucial for accurate results.
  • Vaccine Development: The compound plays a role in vaccine formulation by facilitating the conjugation of antigens to carrier proteins, improving immune response.
  • Research in Cell Biology: It aids in studying cell interactions and signaling pathways by labeling proteins, allowing researchers to visualize and track cellular processes.
  • Therapeutic Development: This chemical is valuable in creating targeted therapies, especially in cancer treatment, by enabling the attachment of therapeutic agents to specific cell types.

Citations