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Catalog Number:
38489
CAS Number:
1263-89-4
Paromomycin sulfate salt powder
Grade:
suitable for cell culture
Synonym(s):
Aminosidine sulfate
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$30.85 /1G
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Product Information

Paromomycin sulfate salt powder is an aminoglycoside antibiotic renowned for its effectiveness against a variety of bacterial infections, particularly those caused by Gram-negative bacteria. This compound is widely utilized in both clinical and research settings, primarily for its role in treating infections such as visceral leishmaniasis and certain types of tuberculosis. Its unique mechanism of action involves binding to the bacterial ribosome, inhibiting protein synthesis, which makes it a valuable tool in the fight against resistant strains of bacteria.

In addition to its therapeutic applications, paromomycin sulfate salt powder is also employed in laboratory research, particularly in studies related to antibiotic resistance and microbial genetics. Its stability and solubility in aqueous solutions enhance its usability in various formulations, making it suitable for both injectable and oral preparations. Researchers and healthcare professionals appreciate its broad-spectrum activity and low toxicity profile, which allows for safe administration in diverse patient populations.

Synonyms
Aminosidine sulfate
CAS Number
1263-89-4
Grade
suitable for cell culture
Molecular Formula
C23H45N5O14·H2SO4
Molecular Weight
713.7
MDL Number
MFCD00079278
PubChem ID
5458443
Appearance
White to yellowish powder
Optical Rotation
[a]20D = 50 - 55 °
Conditions
Store at RT
Potency
≥ 675 µg/mg (on dried basis)
General Information
Synonyms
Aminosidine sulfate
CAS Number
1263-89-4
Grade
suitable for cell culture
Molecular Formula
C23H45N5O14·H2SO4
Molecular Weight
713.7
MDL Number
MFCD00079278
PubChem ID
5458443
Appearance
White to yellowish powder
Optical Rotation
[a]20D = 50 - 55 °
Conditions
Store at RT
Potency
≥ 675 µg/mg (on dried basis)
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Paromomycin sulfate salt powder is widely utilized in research focused on:

  • Antibiotic Development: This compound is used in the formulation of antibiotics, particularly for treating infections caused by resistant bacteria. Its effectiveness against a range of pathogens makes it a valuable tool in pharmaceutical research.
  • Parasitology Studies: It plays a crucial role in studying parasitic infections, particularly leishmaniasis and amoebiasis. Researchers use it to evaluate therapeutic efficacy and understand drug resistance mechanisms.
  • Veterinary Medicine: The compound is applied in veterinary practices to treat gastrointestinal infections in livestock and pets, ensuring animal health and productivity.
  • Drug Formulation: Paromomycin is often included in combination therapies, enhancing the effectiveness of other medications while reducing the likelihood of resistance development.
  • Clinical Trials: It is frequently used in clinical research to assess new treatment protocols for various infectious diseases, providing insights that can lead to improved patient outcomes.

Citations