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Catalog Number:
38480
CAS Number:
108321-42-2
G 418 disulfate salt powder
Grade:
suitable for cell culture
Synonym(s):
Antibiotic G418, Aminoglycoside antibiotic
Documents
$68.50 /1G
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Product Information

G 418 disulfate salt powder is a potent aminoglycoside antibiotic widely utilized in molecular biology and genetic research. This compound is particularly effective in selecting and maintaining mammalian cells that have been transfected with genes conferring resistance to G 418, making it an invaluable tool in gene expression studies and the development of stable cell lines. Its unique mechanism of action inhibits protein synthesis, allowing researchers to effectively eliminate non-transfected cells, thereby enhancing the efficiency of transfection experiments.

In addition to its applications in cell culture, G 418 disulfate salt powder is also employed in the production of transgenic animals and in various gene therapy protocols. The compound's high efficacy and specificity make it a preferred choice for researchers looking to ensure the successful integration and expression of foreign genes. With its proven track record in enhancing gene delivery systems, G 418 disulfate salt powder stands out as a critical reagent in advancing genetic research and biotechnological applications.

Synonyms
Antibiotic G418, Aminoglycoside antibiotic
CAS Number
108321-42-2
Grade
suitable for cell culture
Molecular Formula
C20H40N4O10·2H2SO4
Molecular Weight
692.7
MDL Number
MFCD05664725
PubChem ID
16760463
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Potency
≥ 700 mg/mg (anhydrous basis)
General Information
Synonyms
Antibiotic G418, Aminoglycoside antibiotic
CAS Number
108321-42-2
Grade
suitable for cell culture
Molecular Formula
C20H40N4O10·2H2SO4
Molecular Weight
692.7
MDL Number
MFCD05664725
PubChem ID
16760463
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Potency
≥ 700 mg/mg (anhydrous basis)
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

G 418 disulfate salt powder is widely utilized in research focused on:

  • Gene Therapy: This compound is commonly used in gene therapy applications, particularly for selecting genetically modified cells. It helps in the identification of successfully transfected cells by conferring resistance to certain antibiotics.
  • Cell Culture: In the field of cell biology, it is employed to maintain and select stable cell lines that express specific genes. This is crucial for producing recombinant proteins and studying gene function.
  • Pharmaceutical Development: Researchers utilize this compound in drug development processes, particularly in screening for effective compounds that can target specific cellular pathways.
  • Transgenic Animal Production: G 418 is instrumental in the creation of transgenic animals, aiding in the selection of embryos that carry desired genetic modifications, which is vital for agricultural and biomedical research.
  • Biotechnology Research: It plays a significant role in various biotechnological applications, including the production of monoclonal antibodies and other biopharmaceuticals, enhancing the efficiency of these processes.

Citations