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Catalog Number:
38471
CAS Number:
50-76-0
Actinomycin D from Streptomyces species
Grade:
suitable for cell culture
Purity:
≥ 95% (HPLC)
Synonym(s):
Dactinomycin, Actinomycin C1
Hazmat
Documents
$38.46 /5MG
Pack Size Availability Price
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Product Information
Synonyms
Dactinomycin, Actinomycin C1
CAS Number
50-76-0
Purity
≥ 95% (HPLC)
Grade
suitable for cell culture
Molecular Formula
C62H86N12O16
Molecular Weight
0
MDL Number
MFCD00005033
PubChem ID
2019
Melting Point
243 - 248 °C
Appearance
Bright red crystalline powder
Optical Rotation
[a]20D = -292 to -317 °
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Dactinomycin, Actinomycin C1
CAS Number
50-76-0
Purity
≥ 95% (HPLC)
Grade
suitable for cell culture
Molecular Formula
C62H86N12O16
Molecular Weight
0
MDL Number
MFCD00005033
PubChem ID
2019
Melting Point
243 - 248 °C
Appearance
Bright red crystalline powder
Optical Rotation
[a]20D = -292 to -317 °
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Actinomycin D from Streptomyces species is widely utilized in research focused on:

  • Cancer Treatment: This compound is a potent anti-cancer agent, commonly used in chemotherapy regimens for various types of tumors, including Wilms' tumor and rhabdomyosarcoma, providing effective treatment options for patients.
  • Gene Expression Studies: Researchers employ Actinomycin D to inhibit RNA synthesis, allowing them to study gene expression and regulation mechanisms in cellular biology, which is crucial for understanding diseases.
  • Antibiotic Development: Its unique structure and mechanism of action inspire the development of new antibiotics, making it a valuable compound in the fight against antibiotic-resistant bacteria.
  • Cell Cycle Research: Actinomycin D is used to investigate the effects of transcriptional inhibition on cell cycle progression, helping scientists understand cellular responses to stress and potential therapeutic targets.
  • Biotechnology Applications: In biomanufacturing, it serves as a tool for optimizing the production of recombinant proteins by controlling gene expression, enhancing yield and efficiency in industrial processes.

Citations