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Catalog Number:
38448
CAS Number:
79660-72-3
Fleroxacin
Purity:
≥ 98% (Assay by titration)
Synonym(s):
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylicacid, Megalone
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Product Information

Fleroxacin is a potent fluoroquinolone antibiotic known for its broad-spectrum activity against a variety of bacterial infections. This compound is particularly effective in treating respiratory tract infections, urinary tract infections, and skin infections, making it a valuable asset in both clinical and research settings. Its unique structure, featuring two fluorine atoms and a piperazine moiety, enhances its antibacterial efficacy while reducing the likelihood of resistance development. Fleroxacin's ability to penetrate bacterial cell membranes allows for effective targeting of both Gram-positive and Gram-negative bacteria, which is crucial in today’s healthcare landscape where antibiotic resistance is a growing concern.

In addition to its therapeutic applications, Fleroxacin is also utilized in pharmaceutical research to develop new formulations and delivery methods. Researchers appreciate its favorable pharmacokinetic properties, which include good oral bioavailability and a relatively long half-life, facilitating less frequent dosing regimens. This compound's versatility and effectiveness make it a preferred choice for healthcare professionals looking to combat bacterial infections while minimizing the risk of resistance.

Synonyms
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylicacid, Megalone
CAS Number
79660-72-3
Purity
≥ 98% (Assay by titration)
Molecular Formula
C17H18F3N3O3
Molecular Weight
369.34
MDL Number
MFCD00864880
PubChem ID
3357
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylicacid, Megalone
CAS Number
79660-72-3
Purity
≥ 98% (Assay by titration)
Molecular Formula
C17H18F3N3O3
Molecular Weight
369.34
MDL Number
MFCD00864880
PubChem ID
3357
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fleroxacin is widely utilized in research focused on:

  • Antibiotic Development: As a fluoroquinolone antibiotic, it is used in the development of new antibacterial agents, providing a framework for creating drugs that combat resistant bacterial strains.
  • Clinical Applications: Fleroxacin is effective in treating various bacterial infections, particularly in respiratory and urinary tract infections, making it valuable in clinical settings.
  • Pharmaceutical Research: It serves as a model compound in pharmaceutical studies to understand drug interactions and pharmacokinetics, aiding in the design of more effective medications.
  • Veterinary Medicine: The compound is also applied in veterinary practices to treat infections in animals, showcasing its versatility across different fields of medicine.
  • Research on Resistance Mechanisms: Fleroxacin is used in studies investigating bacterial resistance mechanisms, helping researchers develop strategies to overcome antibiotic resistance.

Citations