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Catalog Number:
38433
CAS Number:
103060-53-3
Daptomycin
Purity:
95 - 102% (Assay on anhydrous basis)
Documents
$40.00 /25MG
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Product Information

Daptomycin is a powerful lipopeptide antibiotic renowned for its efficacy against a wide range of Gram-positive bacteria, including resistant strains such as MRSA (Methicillin-resistant Staphylococcus aureus). This compound is particularly valuable in clinical settings for treating complicated skin and skin structure infections, as well as bacteremia and endocarditis. Its unique mechanism of action disrupts bacterial cell membrane integrity, leading to rapid cell death, making it a critical option in the fight against antibiotic resistance.

In addition to its therapeutic applications, Daptomycin's favorable pharmacokinetic profile allows for once-daily dosing, enhancing patient compliance and treatment outcomes. Researchers are also exploring its potential in combination therapies to broaden its spectrum of activity and improve efficacy against biofilm-associated infections. With its proven track record in clinical use and ongoing research into its capabilities, Daptomycin stands out as a vital tool in modern antimicrobial therapy.

CAS Number
103060-53-3
Purity
95 - 102% (Assay on anhydrous basis)
Molecular Formula
C72H101N17O26
Molecular Weight
1620.69
MDL Number
MFCD08282794
PubChem ID
16129688
Appearance
Pale yellow to yellow powder
Optical Rotation
[a]D20 = 17 - 25 °
Conditions
Store at < -20 °C
General Information
CAS Number
103060-53-3
Purity
95 - 102% (Assay on anhydrous basis)
Molecular Formula
C72H101N17O26
Molecular Weight
1620.69
MDL Number
MFCD08282794
PubChem ID
16129688
Appearance
Pale yellow to yellow powder
Optical Rotation
[a]D20 = 17 - 25 °
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Daptomycin is widely utilized in research focused on:

  • Antibiotic Therapy: This compound is primarily used in treating serious skin and soft tissue infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Its unique mechanism of action makes it effective where other antibiotics may fail.
  • Clinical Research: Daptomycin is a subject of ongoing clinical studies to explore its efficacy against various bacterial infections, including endocarditis and osteomyelitis. Researchers are investigating its potential in combination therapies to enhance treatment outcomes.
  • Pharmaceutical Development: The compound serves as a model for developing new antibiotics. Its structure and function inform the design of novel agents that can combat antibiotic resistance, a growing concern in healthcare.
  • Veterinary Medicine: Daptomycin is also being explored for use in veterinary applications, particularly for treating infections in livestock and pets, ensuring animal health and welfare.
  • Biotechnology: In biotechnological applications, daptomycin is used in the development of biosensors and diagnostic tools to detect bacterial infections quickly and accurately, improving patient management.

Citations