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Catalog Number:
38424
CAS Number:
58207-19-5
Clindamycin hydrochloride monohydrate
Purity:
≥ 98% (Assay by Titration)
Synonym(s):
(7S)-7-Chloro-7-deoxylincomycin hydrochloride monohydrate
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Product Information

Clindamycin hydrochloride monohydrate is a potent antibiotic belonging to the lincosamide class, primarily used in the treatment of various bacterial infections. This compound is particularly effective against anaerobic bacteria and certain protozoa, making it a valuable option in clinical settings for treating serious infections such as those caused by Streptococcus and Staphylococcus species. Its unique mechanism of action involves inhibiting bacterial protein synthesis, which is crucial in combating resistant strains. Researchers and healthcare professionals appreciate its versatility in both oral and topical formulations, allowing for tailored treatment approaches in diverse patient populations.

In addition to its therapeutic applications, clindamycin hydrochloride monohydrate is also utilized in veterinary medicine and can be found in formulations for treating infections in animals. Its stability and solubility enhance its usability in various pharmaceutical preparations, ensuring effective delivery and patient compliance. With a strong safety profile and a well-established history of efficacy, this compound remains a cornerstone in antibiotic therapy, particularly for patients with penicillin allergies or those requiring alternative treatment options.

Synonyms
(7S)-7-Chloro-7-deoxylincomycin hydrochloride monohydrate
CAS Number
58207-19-5
Purity
≥ 98% (Assay by Titration)
Molecular Formula
C18H33ClN2O5S·HCl·H2O
Molecular Weight
479.46
MDL Number
MFCD06411091
PubChem ID
20159208
Melting Point
142 - 144 °C
Appearance
White to almost white powder to crystal
Optical Rotation
140 - 147 ° (C=2, H2O) (calculated on anhydrous substance)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(7S)-7-Chloro-7-deoxylincomycin hydrochloride monohydrate
CAS Number
58207-19-5
Purity
≥ 98% (Assay by Titration)
Molecular Formula
C18H33ClN2O5S·HCl·H2O
Molecular Weight
479.46
MDL Number
MFCD06411091
PubChem ID
20159208
Melting Point
142 - 144 °C
Appearance
White to almost white powder to crystal
Optical Rotation
140 - 147 ° (C=2, H2O) (calculated on anhydrous substance)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Clindamycin hydrochloride monohydrate is widely utilized in research focused on

  • Antibiotic Treatments: It is primarily used in the treatment of various bacterial infections, particularly those caused by anaerobic bacteria. This makes it essential in both clinical settings and research on antibiotic resistance.
  • Dermatology Applications: Commonly prescribed for acne and other skin infections, it helps reduce inflammation and bacterial load, providing effective solutions for dermatologists and skincare researchers.
  • Veterinary Medicine: This compound is also used in veterinary practices to treat infections in animals, showcasing its versatility and importance in animal health.
  • Research on Drug Resistance: Clindamycin is a key compound in studies aimed at understanding and overcoming antibiotic resistance, making it invaluable for microbiologists and pharmaceutical researchers.
  • Combination Therapies: It is often used in combination with other antibiotics to enhance efficacy against resistant strains, providing a strategic advantage in treatment protocols.

Citations