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Catalog Number:
38401
CAS Number:
62013-04-1
Dirithromycin
Purity:
≥ 98% (HPLC)
Synonym(s):
[9S(R)]-9-Deoxo-11-deoxy-9,11-[imino[2-(2-methoxyethoxy)ethylidene]oxy]erythromycin, LY-237216
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$156.33 /1G
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Product Information

Dirithromycin is a macrolide antibiotic renowned for its effectiveness against a variety of bacterial infections. This compound is particularly valuable in the treatment of respiratory tract infections, skin infections, and certain sexually transmitted diseases. Its unique structure allows it to inhibit bacterial protein synthesis, making it a potent option for combating resistant strains of bacteria. Dirithromycin is often favored for its favorable pharmacokinetic properties, including good oral bioavailability and a long half-life, which can lead to less frequent dosing compared to other antibiotics.

In clinical settings, Dirithromycin has been successfully utilized in treating infections caused by organisms such as Streptococcus pneumoniae and Haemophilus influenzae. Its application extends to both outpatient and inpatient settings, providing healthcare professionals with a reliable option for managing infections. The compound's ability to penetrate tissues effectively enhances its therapeutic potential, making it a preferred choice in various treatment regimens. With its proven efficacy and safety profile, Dirithromycin remains a critical tool in the fight against bacterial infections.

Synonyms
[9S(R)]-9-Deoxo-11-deoxy-9,11-[imino[2-(2-methoxyethoxy)ethylidene]oxy]erythromycin, LY-237216
CAS Number
62013-04-1
Purity
≥ 98% (HPLC)
Molecular Formula
C42H78N2O14
Molecular Weight
835.09
MDL Number
MFCD00865041
PubChem ID
4580358
Melting Point
186 - 190 °C
Appearance
White to almost white powder to crystal
Optical Rotation
-85 to -90 ° (C=1, MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
[9S(R)]-9-Deoxo-11-deoxy-9,11-[imino[2-(2-methoxyethoxy)ethylidene]oxy]erythromycin, LY-237216
CAS Number
62013-04-1
Purity
≥ 98% (HPLC)
Molecular Formula
C42H78N2O14
Molecular Weight
835.09
MDL Number
MFCD00865041
PubChem ID
4580358
Melting Point
186 - 190 °C
Appearance
White to almost white powder to crystal
Optical Rotation
-85 to -90 ° (C=1, MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Dirithromycin is widely utilized in research focused on:

  • Antibiotic Therapy: This compound is primarily used as an antibiotic to treat various bacterial infections, particularly respiratory tract infections. Its effectiveness against resistant strains makes it a valuable option in clinical settings.
  • Pharmaceutical Development: Dirithromycin serves as a model compound in the development of new macrolide antibiotics, helping researchers to innovate and improve existing treatments.
  • Microbiology Studies: In laboratories, it is used to study the mechanisms of bacterial resistance, providing insights that can lead to the development of more effective antibiotics.
  • Veterinary Medicine: This chemical is also applied in veterinary settings to treat infections in animals, ensuring their health and well-being.
  • Formulation Research: Dirithromycin is explored in formulation studies to enhance drug delivery systems, improving the bioavailability and efficacy of antibiotic treatments.

Citations