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Catalog Number:
38379
CAS Number:
119478-56-7
Meropenem trihydrate
Purity:
98 - 101% (Assay : Anhydrous basis)
Synonym(s):
(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylicacid trihydrate
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Product Information

Meropenem trihydrate is a broad-spectrum carbapenem antibiotic, renowned for its efficacy against a wide range of Gram-positive and Gram-negative bacteria, including those resistant to other antibiotics. This compound is particularly valuable in the treatment of severe infections, such as those caused by multi-drug resistant organisms, making it a critical option in hospital settings. Its unique structure allows it to penetrate bacterial cell walls effectively, ensuring rapid action against pathogens. Meropenem trihydrate is commonly utilized in the treatment of complicated intra-abdominal infections, meningitis, and pneumonia, providing healthcare professionals with a reliable tool in combating serious infections.

In addition to its therapeutic applications, Meropenem trihydrate's stability and solubility make it suitable for various formulations, including intravenous administration. Researchers are also exploring its potential in combination therapies to enhance efficacy and reduce resistance development. With its proven track record and versatility, Meropenem trihydrate remains an essential compound in modern medicine, offering significant benefits in both clinical and research settings.

Synonyms
(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylicacid trihydrate
CAS Number
119478-56-7
Purity
98 - 101% (Assay : Anhydrous basis)
Molecular Formula
C17H25N3O5S·3H2O
Molecular Weight
437.51
MDL Number
MFCD08600005
PubChem ID
22126008
Appearance
White to yellowish crystalline powder
Optical Rotation
[a]D20 = -17 to -21 °
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylicacid trihydrate
CAS Number
119478-56-7
Purity
98 - 101% (Assay : Anhydrous basis)
Molecular Formula
C17H25N3O5S·3H2O
Molecular Weight
437.51
MDL Number
MFCD08600005
PubChem ID
22126008
Appearance
White to yellowish crystalline powder
Optical Rotation
[a]D20 = -17 to -21 °
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Meropenem trihydrate is widely utilized in research focused on:

  • Antibiotic Development: This compound is a broad-spectrum antibiotic used in the treatment of severe bacterial infections. Its effectiveness against resistant strains makes it a critical component in antibiotic research and development.
  • Pharmaceutical Formulations: In the pharmaceutical industry, it is used to formulate injectable medications, providing a stable and effective treatment option for patients with serious infections.
  • Clinical Trials: Researchers often use Meropenem trihydrate in clinical trials to evaluate its efficacy and safety in treating conditions like pneumonia and meningitis, contributing to advancements in medical treatments.
  • Infection Control: Hospitals utilize this antibiotic in infection control protocols, particularly for patients undergoing surgery or those with compromised immune systems, reducing the risk of postoperative infections.
  • Comparative Studies: It serves as a benchmark in studies comparing the effectiveness of new antibiotics, helping to identify potential alternatives for treating resistant bacterial infections.

Citations