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Catalog Number:
38372
CAS Number:
165800-06-6
Zoledronic acid monohydrate
Purity:
≥ 98% (HPLC)
Synonym(s):
1-Hydroxy-2-(1-imidazolyl)ethane-1,1-diphosphonic acidmonohydrate
Documents
$118.08 /1G
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Product Information

Zoledronic acid monohydrate is a potent bisphosphonate compound widely recognized for its efficacy in treating various bone-related conditions, including osteoporosis and Paget's disease. This compound works by inhibiting osteoclast-mediated bone resorption, thereby helping to maintain bone density and strength. Its unique mechanism of action makes it particularly valuable in oncology, where it is used to prevent skeletal-related events in patients with bone metastases. Researchers and healthcare professionals appreciate its high bioavailability and long half-life, which contribute to its effectiveness in long-term treatment regimens.

In addition to its therapeutic applications, zoledronic acid monohydrate is also utilized in research settings to study bone metabolism and the effects of bisphosphonates on mineralization processes. Its ability to bind to hydroxyapatite in bone tissue enhances its relevance in both clinical and laboratory environments. With its proven track record and versatility, zoledronic acid monohydrate stands out as a critical compound for professionals focused on bone health and related research.

Synonyms
1-Hydroxy-2-(1-imidazolyl)ethane-1,1-diphosphonic acidmonohydrate
CAS Number
165800-06-6
Purity
≥ 98% (HPLC)
Molecular Formula
C5H10N2O7P2·H2O
Molecular Weight
290.11
MDL Number
MFCD08448695
PubChem ID
121586
Melting Point
245 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-Hydroxy-2-(1-imidazolyl)ethane-1,1-diphosphonic acidmonohydrate
CAS Number
165800-06-6
Purity
≥ 98% (HPLC)
Molecular Formula
C5H10N2O7P2·H2O
Molecular Weight
290.11
MDL Number
MFCD08448695
PubChem ID
121586
Melting Point
245 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Zoledronic acid monohydrate is widely utilized in research focused on:

  • Treatment of Osteoporosis: This compound is commonly prescribed to strengthen bones in patients with osteoporosis, reducing the risk of fractures.
  • Management of Bone Metastases: In oncology, it helps manage bone pain and complications in patients with cancer that has spread to the bones, improving quality of life.
  • Prevention of Skeletal-Related Events: It is effective in preventing skeletal-related events in patients with multiple myeloma or solid tumors, making it essential in cancer care.
  • Research in Bone Health: Researchers use it to study bone remodeling and the effects of bisphosphonates on bone density, contributing to advancements in bone health therapies.
  • Veterinary Medicine: Zoledronic acid is also explored in veterinary applications for treating bone diseases in animals, showcasing its versatility beyond human medicine.

Citations