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Catalog Number:
38346
CAS Number:
38194-50-2
Sulindac
Purity:
≥ 98% (HPLC)
Synonym(s):
(Z-5-Fluoro-2-methyl-1-[(p-methylsulfinyl)benzylidene]-1H-indene-3-acetic acid, (Z-2-[5-Fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl]acetic acid
Hazmat
Documents
$100.05 /10G
Pack Size Availability Price
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Product Information

Sulindac is a non-steroidal anti-inflammatory drug (NSAID) renowned for its effectiveness in alleviating pain and inflammation. This compound is particularly beneficial in the treatment of conditions such as arthritis, gout, and other musculoskeletal disorders. Its unique structure allows for a dual mechanism of action, providing both analgesic and anti-inflammatory effects, making it a preferred choice for patients seeking relief from chronic pain.

In addition to its therapeutic applications, Sulindac has been studied for its potential chemopreventive properties, particularly in colorectal cancer. Researchers have explored its ability to inhibit tumor growth, showcasing its relevance in oncology. With its favorable pharmacokinetic profile, Sulindac is often favored for its ease of use and effectiveness in various clinical settings. This compound stands out among NSAIDs due to its selective inhibition of cyclooxygenase enzymes, which may lead to a reduced risk of gastrointestinal side effects compared to traditional NSAIDs, making it a valuable option for long-term management of pain and inflammation.

Synonyms
(Z-5-Fluoro-2-methyl-1-[(p-methylsulfinyl)benzylidene]-1H-indene-3-acetic acid, (Z-2-[5-Fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl]acetic acid
CAS Number
38194-50-2
Purity
≥ 98% (HPLC)
Molecular Formula
C20H17FO3S
Molecular Weight
356.41
MDL Number
MFCD00599589
PubChem ID
5352
Melting Point
182 - 186 ?C
Appearance
Light yellow to brown powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(Z-5-Fluoro-2-methyl-1-[(p-methylsulfinyl)benzylidene]-1H-indene-3-acetic acid, (Z-2-[5-Fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl]acetic acid
CAS Number
38194-50-2
Purity
≥ 98% (HPLC)
Molecular Formula
C20H17FO3S
Molecular Weight
356.41
MDL Number
MFCD00599589
PubChem ID
5352
Melting Point
182 - 186 ?C
Appearance
Light yellow to brown powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Sulindac is widely utilized in research focused on:

  • Pain Management: Commonly used as a non-steroidal anti-inflammatory drug (NSAID), it effectively alleviates pain and inflammation, making it valuable in treating conditions like arthritis.
  • Cancer Research: Studies have shown that Sulindac may have chemopreventive properties, particularly in colorectal cancer, providing a potential avenue for researchers exploring cancer therapies.
  • Cardiovascular Health: Its anti-inflammatory properties can be beneficial in managing cardiovascular diseases, offering a dual approach to pain relief and heart health.
  • Veterinary Medicine: Sulindac is also used in veterinary applications for pain relief in animals, showcasing its versatility across species.
  • Drug Formulation: The compound's unique properties allow for the development of various formulations, enhancing patient compliance and treatment outcomes.

Citations