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Catalog Number:
38323
CAS Number:
163451-81-8
Teriflunomide
Purity:
≥ 98% (GC)
Synonym(s):
N-[4-(Trifluoromethyl)phenyl]-2-cyano-3-hydroxycrotonamide, (Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
Documents
$189.58 /100MG
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Product Information

Teriflunomide is a potent immunomodulatory agent primarily utilized in the treatment of multiple sclerosis (MS). This compound functions by inhibiting the proliferation of activated lymphocytes, thereby reducing the inflammatory processes associated with MS. Its unique mechanism of action makes it a valuable option for patients seeking to manage their condition effectively. Teriflunomide is recognized for its favorable pharmacokinetic profile, allowing for once-daily oral administration, which enhances patient compliance.

In addition to its primary application in MS, Teriflunomide is being explored for potential uses in other autoimmune disorders due to its ability to modulate immune responses. Researchers appreciate its low toxicity and the absence of significant drug interactions, making it a safer alternative compared to other immunosuppressants. With ongoing studies, Teriflunomide holds promise for expanding its therapeutic applications, providing a versatile tool for healthcare professionals in managing complex autoimmune conditions.

Synonyms
N-[4-(Trifluoromethyl)phenyl]-2-cyano-3-hydroxycrotonamide, (Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
CAS Number
163451-81-8
Purity
≥ 98% (GC)
Molecular Formula
C12H9F3N2O2
Molecular Weight
270.21
MDL Number
MFCD00910058
PubChem ID
54677977
Melting Point
227 - 231 °C
Appearance
White to almost white powder to crystal
Conditions
Store at < -20 °C
General Information
Synonyms
N-[4-(Trifluoromethyl)phenyl]-2-cyano-3-hydroxycrotonamide, (Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
CAS Number
163451-81-8
Purity
≥ 98% (GC)
Molecular Formula
C12H9F3N2O2
Molecular Weight
270.21
MDL Number
MFCD00910058
PubChem ID
54677977
Melting Point
227 - 231 °C
Appearance
White to almost white powder to crystal
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Teriflunomide is widely utilized in research focused on

  • Multiple Sclerosis Treatment: This compound is primarily used as an oral medication for treating relapsing forms of multiple sclerosis (MS), helping to reduce the frequency of relapses and slow disease progression.
  • Immunomodulation: Teriflunomide works by modulating the immune system, making it beneficial for researchers studying autoimmune diseases and developing new therapies.
  • Pharmaceutical Development: Its unique mechanism of action provides a valuable model for pharmaceutical companies looking to create new immunosuppressive drugs with fewer side effects compared to traditional therapies.
  • Research in Cancer Therapy: Investigations are ongoing into its potential applications in oncology, particularly in enhancing the efficacy of certain cancer treatments through immune system modulation.
  • Comparative Effectiveness Studies: Researchers are using teriflunomide in clinical trials to compare its effectiveness and safety profile against other MS treatments, providing crucial data for healthcare providers.

Citations