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Catalog Number:
38320
CAS Number:
145821-59-6
Tiagabine hydrochloride
Purity:
≥ 99% (HPLC)
Synonym(s):
(-)-(R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecoticacid hydrochloride, (3R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylicacid hydrochloride
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$106.96 /50MG
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Product Information

Tiagabine hydrochloride is a potent pharmaceutical compound primarily utilized as an anticonvulsant in the treatment of epilepsy. This selective GABA reuptake inhibitor enhances the inhibitory effects of GABA in the brain, making it particularly effective for patients with partial seizures. Its unique mechanism of action allows for improved seizure control, providing significant relief for individuals who may not respond adequately to other antiepileptic medications.

In addition to its primary use in epilepsy management, Tiagabine hydrochloride has shown promise in treating anxiety disorders and other neurological conditions, highlighting its versatility in therapeutic applications. Researchers and healthcare professionals appreciate its ability to target specific pathways in the central nervous system, offering a tailored approach to treatment. With a favorable safety profile and a well-established efficacy, Tiagabine hydrochloride stands out as a valuable option for both clinicians and patients seeking effective seizure management.

Synonyms
(-)-(R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecoticacid hydrochloride, (3R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylicacid hydrochloride
CAS Number
145821-59-6
Purity
≥ 99% (HPLC)
Molecular Formula
C20H25NO2S2·HCl
Molecular Weight
412.0
MDL Number
MFCD07369025
PubChem ID
22058231
Melting Point
189 - 194 °C
Appearance
White to light yellow powder to crystal
Optical Rotation
-9 to -12 ° (C=1, H2O)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(-)-(R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecoticacid hydrochloride, (3R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylicacid hydrochloride
CAS Number
145821-59-6
Purity
≥ 99% (HPLC)
Molecular Formula
C20H25NO2S2·HCl
Molecular Weight
412.0
MDL Number
MFCD07369025
PubChem ID
22058231
Melting Point
189 - 194 °C
Appearance
White to light yellow powder to crystal
Optical Rotation
-9 to -12 ° (C=1, H2O)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tiagabine hydrochloride is widely utilized in research focused on

  • Epilepsy Treatment: It is primarily used as an anticonvulsant medication for treating epilepsy, helping to reduce the frequency of seizures in patients.
  • Neuropharmacology Studies: Researchers use it to study the mechanisms of GABA uptake inhibition, which can provide insights into various neurological disorders.
  • Psychiatric Research: The compound is explored for its potential effects on anxiety and depression, offering a pathway for developing new treatments.
  • Pharmaceutical Formulations: It serves as an important ingredient in drug formulations, ensuring effective delivery and stability of the active compound.
  • Clinical Trials: Tiagabine hydrochloride is often involved in clinical trials aimed at assessing its efficacy and safety in diverse patient populations, contributing to advancements in therapeutic options.

Citations