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Catalog Number:
38299
CAS Number:
144701-48-4
Telmisartan
Grade:
meets USP, NF specification
Purity:
98 - 102% (Assay, on dried basis)
Synonym(s):
4'-[[4-Methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]methyl]biphenyl-2-carboxylicacid, BIBR 277
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Product Information

Telmisartan is a potent angiotensin II receptor antagonist primarily used in the management of hypertension and cardiovascular diseases. This compound is recognized for its ability to effectively lower blood pressure by inhibiting the action of angiotensin II, a hormone that constricts blood vessels. Its unique structure allows for a longer duration of action compared to other antihypertensive agents, making it a preferred choice for patients requiring sustained blood pressure control. Additionally, Telmisartan has shown promise in improving insulin sensitivity and may offer protective benefits against certain cardiovascular complications, making it a valuable option in the treatment of metabolic syndrome.

In the pharmaceutical industry, Telmisartan is often utilized in combination therapies to enhance efficacy and patient compliance. Its favorable pharmacokinetic profile allows for once-daily dosing, which is advantageous for both patients and healthcare providers. Researchers are also exploring its potential applications in nephrology, particularly in protecting renal function in diabetic patients. With its established safety profile and versatility in treatment regimens, Telmisartan stands out as a key player in modern hypertension management.

Synonyms
4'-[[4-Methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]methyl]biphenyl-2-carboxylicacid, BIBR 277
CAS Number
144701-48-4
Purity
98 - 102% (Assay, on dried basis)
Grade
meets USP, NF specification
Molecular Formula
C33H30N4O2
Molecular Weight
514.63
MDL Number
MFCD00918125
PubChem ID
65999
Melting Point
268 - 270 °C
Appearance
White or slightly yellowish crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
4'-[[4-Methyl-6-(1-methyl-1H-benzimidazol-2-yl)-2-propyl-1H-benzimidazol-1-yl]methyl]biphenyl-2-carboxylicacid, BIBR 277
CAS Number
144701-48-4
Purity
98 - 102% (Assay, on dried basis)
Grade
meets USP, NF specification
Molecular Formula
C33H30N4O2
Molecular Weight
514.63
MDL Number
MFCD00918125
PubChem ID
65999
Melting Point
268 - 270 °C
Appearance
White or slightly yellowish crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Telmisartan is widely utilized in research focused on:

  • Hypertension Management: Commonly prescribed for lowering blood pressure, it helps reduce the risk of heart disease and stroke, making it essential in cardiology.
  • Diabetes Protection: Research shows that it may offer protective benefits for diabetic patients by improving insulin sensitivity and reducing cardiovascular risks.
  • Heart Failure Treatment: Used in combination therapies, it aids in managing heart failure symptoms, improving quality of life for patients.
  • Kidney Protection: Effective in slowing the progression of kidney disease in patients with hypertension or diabetes, it is crucial in nephrology.
  • Research on Angiotensin Receptor Blockade: Its mechanism is studied for developing new treatments for various cardiovascular and renal conditions, providing insights into innovative therapies.

Citations