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Catalog Number:
38250
CAS Number:
79902-63-9
Simvastatin
Purity:
≥ 98% (HPLC)
Documents
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Product Information

Simvastatin is a potent statin medication widely recognized for its role in lowering cholesterol levels and managing cardiovascular diseases. This compound functions by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol synthesis in the liver. As a result, Simvastatin effectively reduces low-density lipoprotein (LDL) cholesterol and triglycerides while increasing high-density lipoprotein (HDL) cholesterol. Its clinical applications extend to the prevention of heart attacks and strokes, making it a vital component in the treatment of hyperlipidemia and related conditions.

In addition to its primary use in cholesterol management, Simvastatin has shown promise in various research settings, including studies on its anti-inflammatory properties and potential benefits in other metabolic disorders. Its unique structure allows for effective absorption and bioavailability, making it a preferred choice among healthcare professionals. With a strong safety profile and extensive clinical backing, Simvastatin remains a cornerstone in cardiovascular therapy, offering significant benefits for patients at risk of heart disease.

CAS Number
79902-63-9
Purity
≥ 98% (HPLC)
Molecular Formula
C25H38O5
Molecular Weight
418.57
MDL Number
MFCD00072007
PubChem ID
4677798
Melting Point
127 - 137 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 285 - 300 ° (C=1 in CH3CN)
Conditions
Store at 2 - 8 °C
General Information
CAS Number
79902-63-9
Purity
≥ 98% (HPLC)
Molecular Formula
C25H38O5
Molecular Weight
418.57
MDL Number
MFCD00072007
PubChem ID
4677798
Melting Point
127 - 137 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 285 - 300 ° (C=1 in CH3CN)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Simvastatin is widely utilized in research focused on

  • Cardiovascular Health: Primarily used to lower cholesterol levels, it helps reduce the risk of heart disease. This application is crucial for healthcare providers aiming to improve patient outcomes.
  • Pharmaceutical Development: As a key compound in drug formulation, it serves as a model for developing new statins with improved efficacy and safety profiles, benefiting pharmaceutical researchers.
  • Clinical Studies: Frequently involved in clinical trials assessing its long-term effects on cardiovascular health, providing valuable data for medical professionals and researchers.
  • Combination Therapies: Used in conjunction with other medications to enhance cholesterol management, offering a comprehensive approach for patients with complex health needs.
  • Public Health Initiatives: Plays a role in programs aimed at educating the public about cholesterol management and heart health, supporting community health efforts.

Citations