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Catalog Number:
38233
CAS Number:
147098-20-2
Rosuvastatin calcium
Purity:
≥ 95% (HPLC)
Synonym(s):
(E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid
Documents
$228.24 /200MG
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Product Information

Rosuvastatin calcium is a potent statin medication widely recognized for its efficacy in lowering cholesterol levels and improving cardiovascular health. This compound functions by inhibiting HMG-CoA reductase, an enzyme crucial for cholesterol synthesis in the liver, making it a vital tool in managing hyperlipidemia and reducing the risk of heart disease. Its unique structure allows for enhanced bioavailability and a longer half-life compared to other statins, which translates to more effective dosing regimens for patients.

In clinical settings, Rosuvastatin calcium has been extensively utilized not only for lowering LDL cholesterol but also for raising HDL cholesterol levels, thereby contributing to overall lipid profile improvement. Researchers and healthcare professionals appreciate its role in secondary prevention of cardiovascular events, particularly in patients with a history of heart disease. Additionally, its potential anti-inflammatory properties are being explored, indicating further applications in metabolic syndrome and related conditions. With its proven track record and ongoing research, Rosuvastatin calcium remains a cornerstone in lipid management strategies.

Synonyms
(E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid
CAS Number
147098-20-2
Purity
≥ 95% (HPLC)
Molecular Formula
C44H54CaF2N6O12S2
Molecular Weight
1001.14
MDL Number
MFCD04112702
PubChem ID
16413926
Melting Point
159 - 161 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = -7 to -9 ° (C=1 in CHCl3)
Conditions
Store at < 0 °C
General Information
Synonyms
(E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid
CAS Number
147098-20-2
Purity
≥ 95% (HPLC)
Molecular Formula
C44H54CaF2N6O12S2
Molecular Weight
1001.14
MDL Number
MFCD04112702
PubChem ID
16413926
Melting Point
159 - 161 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = -7 to -9 ° (C=1 in CHCl3)
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Rosuvastatin calcium is widely utilized in research focused on:

  • Cholesterol Management: This compound is primarily used to lower LDL cholesterol levels in patients with hyperlipidemia, making it a key player in cardiovascular health.
  • Cardiovascular Disease Prevention: By reducing cholesterol, it helps prevent heart disease and stroke, which is crucial for healthcare providers aiming to improve patient outcomes.
  • Research on Statins: It serves as a model compound in studies investigating the mechanisms of action and side effects of statins, aiding pharmaceutical research and development.
  • Combination Therapies: Rosuvastatin is often used in combination with other medications to enhance therapeutic effects, particularly in patients with multiple risk factors for heart disease.
  • Clinical Trials: It is frequently involved in clinical trials assessing new formulations or delivery methods, providing valuable data for future treatments.

Citations