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Catalog Number:
38223
CAS Number:
95635-56-6
Ranolazine dihydrochloride
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
4-[2-Hydroxy-3-(o-methoxyphenoxy)propyl]-1-piperazineaceto-2',6'-xylididedihydrochloride, N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamidedihydrochloride
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Product Information

Ranolazine dihydrochloride is a pharmaceutical compound primarily utilized in the management of chronic angina and certain cardiac conditions. This compound functions by inhibiting the late sodium current in cardiac myocytes, which helps to improve myocardial efficiency and reduce the oxygen demand of the heart. Its unique mechanism of action distinguishes it from traditional antianginal therapies, making it a valuable option for patients who do not respond adequately to standard treatments.

In addition to its primary use in cardiology, Ranolazine dihydrochloride is being explored for its potential benefits in other areas, such as heart failure and diabetic cardiomyopathy. Researchers are investigating its role in improving exercise tolerance and quality of life for patients with ischemic heart disease. The compound's favorable safety profile and minimal drug interactions further enhance its appeal in clinical settings, providing healthcare professionals with a reliable therapeutic option for managing complex cardiac conditions.

Synonyms
4-[2-Hydroxy-3-(o-methoxyphenoxy)propyl]-1-piperazineaceto-2',6'-xylididedihydrochloride, N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamidedihydrochloride
CAS Number
95635-56-6
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C24H33N3O4·2HCl
Molecular Weight
500.46
MDL Number
MFCD03788770
PubChem ID
71279
Melting Point
227 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
4-[2-Hydroxy-3-(o-methoxyphenoxy)propyl]-1-piperazineaceto-2',6'-xylididedihydrochloride, N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamidedihydrochloride
CAS Number
95635-56-6
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C24H33N3O4·2HCl
Molecular Weight
500.46
MDL Number
MFCD03788770
PubChem ID
71279
Melting Point
227 °C (dec.)
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ranolazine dihydrochloride is widely utilized in research focused on:

  • Cardiovascular Medicine: Primarily used to treat chronic angina, it helps improve blood flow to the heart, making it essential for cardiologists and healthcare providers.
  • Clinical Trials: Frequently involved in studies assessing its efficacy in treating heart-related conditions, providing valuable data for researchers in the pharmaceutical industry.
  • Combination Therapies: Often studied in conjunction with other cardiovascular drugs to enhance therapeutic outcomes, offering insights into multi-drug regimens for better patient management.
  • Pharmacokinetics Research: Its unique absorption and metabolism profiles are explored to understand drug interactions, benefiting researchers in drug development and safety assessments.
  • Patient Compliance Studies: Investigated for its once-daily dosing regimen, which can improve adherence among patients, an important consideration for healthcare professionals.

Citations