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Catalog Number:
38208
CAS Number:
111974-72-2
Quetiapine hemifumarate
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolhemifumarate, Quetiapine fumarate
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Product Information

Quetiapine hemifumarate is a potent atypical antipsychotic used primarily in the treatment of schizophrenia and bipolar disorder. This compound is recognized for its ability to modulate neurotransmitter activity, particularly serotonin and dopamine, making it effective in managing symptoms such as hallucinations, mood swings, and anxiety. Its unique pharmacological profile allows for a favorable side effect profile compared to traditional antipsychotics, which is particularly beneficial for long-term treatment plans.

In addition to its psychiatric applications, Quetiapine hemifumarate has been explored in research settings for its potential use in treating anxiety disorders and as an adjunct therapy in major depressive disorder. Its versatility and efficacy make it a valuable compound for both clinical and research applications, providing healthcare professionals with a reliable option for patient care. The compound's solubility and stability further enhance its usability in various formulations, ensuring that it meets the diverse needs of the pharmaceutical industry.

Synonyms
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolhemifumarate, Quetiapine fumarate
CAS Number
111974-72-2
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C21H25N3O2S·0.5C4H4O4
Molecular Weight
441.55
MDL Number
MFCD03423782
PubChem ID
441261
Melting Point
172 - 176 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolhemifumarate, Quetiapine fumarate
CAS Number
111974-72-2
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C21H25N3O2S·0.5C4H4O4
Molecular Weight
441.55
MDL Number
MFCD03423782
PubChem ID
441261
Melting Point
172 - 176 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Quetiapine hemifumarate is widely utilized in research focused on:

  • Psychiatric Treatment: This compound is primarily used in the treatment of schizophrenia and bipolar disorder, helping to stabilize mood and reduce psychotic symptoms.
  • Clinical Trials: Researchers often use it in clinical trials to evaluate its efficacy and safety compared to other antipsychotic medications, providing valuable data for mental health therapies.
  • Pharmaceutical Formulations: It is a key ingredient in various pharmaceutical formulations, allowing for effective delivery of the active compound in tablet or liquid form.
  • Research on Side Effects: Studies involving Quetiapine hemifumarate help in understanding its side effects, which is crucial for improving patient safety and medication adherence.
  • Combination Therapies: This compound is also explored in combination with other medications to enhance therapeutic outcomes for patients with complex mental health conditions.

Citations