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Catalog Number:
38197
CAS Number:
171228-49-2
Posaconazole
Purity:
≥ 98% (HPLC)
Synonym(s):
2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
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$62.59 /10MG
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Product Information

Posaconazole is a triazole antifungal agent renowned for its broad-spectrum activity against a variety of fungal pathogens, making it an essential compound in both clinical and research settings. With its unique structure, Posaconazole effectively inhibits the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting their growth and proliferation. This compound is particularly valuable in the treatment and prevention of invasive fungal infections, especially in immunocompromised patients, such as those undergoing chemotherapy or organ transplantation.

In addition to its therapeutic applications, Posaconazole is also utilized in agricultural settings as a fungicide, demonstrating efficacy against various plant pathogens. Its ability to provide systemic protection makes it a preferred choice for crop management, ensuring higher yields and healthier plants. Researchers are continually exploring its potential in combination therapies and novel formulations, highlighting its versatility and importance in both medical and agricultural fields.

Synonyms
2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
CAS Number
171228-49-2
Purity
≥ 98% (HPLC)
Molecular Formula
C37H42F2N8O4
Molecular Weight
700.79
MDL Number
MFCD00941162
PubChem ID
21910730
Melting Point
167 - 171 °C
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]20D
Conditions
Store at < 0 °C
General Information
Synonyms
2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol
CAS Number
171228-49-2
Purity
≥ 98% (HPLC)
Molecular Formula
C37H42F2N8O4
Molecular Weight
700.79
MDL Number
MFCD00941162
PubChem ID
21910730
Melting Point
167 - 171 °C
Appearance
White to light yellow powder to crystal
Optical Rotation
[a]20D
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Posaconazole is widely utilized in research focused on:

  • Antifungal Treatments: This compound is primarily used in the medical field for the treatment of invasive fungal infections, particularly in immunocompromised patients. Its effectiveness against a broad spectrum of fungi makes it a critical option in hospitals.
  • Pharmaceutical Development: Researchers leverage Posaconazole in drug formulation studies, exploring its pharmacokinetics and interactions with other medications, which is essential for developing combination therapies.
  • Clinical Trials: It plays a significant role in clinical research aimed at understanding its efficacy and safety in various patient populations, contributing to evidence-based medicine.
  • Veterinary Medicine: The compound is also applied in veterinary settings for treating fungal infections in animals, showcasing its versatility beyond human medicine.
  • Research on Drug Resistance: Scientists study Posaconazole to investigate mechanisms of antifungal resistance, helping to inform future treatment strategies and improve patient outcomes.

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Safety Data Sheets (SDS)

The SDS provides comprehensive safety information on handling, storage, and disposal of the product.

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Safety Data Sheets (SDS)

The SDS provides comprehensive safety information on handling, storage, and disposal of the product.

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Product Specification (PS)

The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

*Catalog Number
The Catalog Number is a five-digit number located on the product label near the product name, and also in your order confirmation email. Exclude any hyphens or size information. Ex. 01578
*Lot Number
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Certificates Of Origin (COO)

This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.

*Catalog Number
The Catalog Number is a five-digit number located on the product label near the product name, and also in your order confirmation email. Exclude any hyphens or size information. Ex. 01578
*Lot Number
The Lot Number is a multi-digit number that can be found on the product label or invoice. Ex. 12345-12345
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