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Catalog Number:
38158
CAS Number:
53179-13-8
Pirfenidone
Purity:
≥ 98% (GC)
Synonym(s):
5-Methyl-1-phenyl-2-pyridone
Documents
$70.91 /100MG
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Product Information

Pirfenidone is a versatile compound recognized for its significant role in the treatment of idiopathic pulmonary fibrosis (IPF), a progressive lung disease. This small molecule has garnered attention for its ability to reduce fibrosis and inflammation, making it a valuable asset in respiratory medicine. With its unique mechanism of action, Pirfenidone not only inhibits fibroblast proliferation but also modulates the production of pro-fibrotic cytokines, which are crucial in the pathogenesis of fibrotic diseases. Researchers and healthcare professionals appreciate its efficacy in improving lung function and quality of life for patients suffering from chronic lung conditions.

In addition to its therapeutic applications, Pirfenidone is also being explored in various research settings, including studies focused on its potential benefits in other fibrotic diseases and its role in cellular signaling pathways. Its favorable pharmacokinetic profile and relatively low side effect burden compared to other treatments make it an attractive option for clinicians. As the understanding of Pirfenidone's mechanisms continues to evolve, its applications in both clinical and research environments are expected to expand, offering new hope for patients with fibrotic diseases.

Synonyms
5-Methyl-1-phenyl-2-pyridone
CAS Number
53179-13-8
Purity
≥ 98% (GC)
Molecular Formula
C12H11NO
Molecular Weight
185.23
MDL Number
MFCD00866047
PubChem ID
40632
Melting Point
107 - 111 °C
Appearance
White to light yellow to green powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-Methyl-1-phenyl-2-pyridone
CAS Number
53179-13-8
Purity
≥ 98% (GC)
Molecular Formula
C12H11NO
Molecular Weight
185.23
MDL Number
MFCD00866047
PubChem ID
40632
Melting Point
107 - 111 °C
Appearance
White to light yellow to green powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pirfenidone is widely utilized in research focused on

  • Treatment of Idiopathic Pulmonary Fibrosis (IPF): This compound is primarily used in the management of IPF, a progressive lung disease. It helps slow down the decline in lung function, improving patients' quality of life.
  • Anti-fibrotic Research: Researchers are exploring its potential in various fibrotic diseases beyond IPF, such as liver fibrosis and kidney fibrosis, making it a valuable compound in developing new therapies.
  • Clinical Trials: Pirfenidone is frequently involved in clinical trials aimed at understanding its efficacy and safety in treating other chronic inflammatory conditions, providing critical data for future medical advancements.
  • Combination Therapies: It is being studied in combination with other drugs to enhance therapeutic outcomes for patients with complex diseases, showcasing its versatility in treatment regimens.
  • Pharmaceutical Development: The compound serves as a model for developing new anti-fibrotic agents, helping pharmaceutical companies innovate and expand their product lines in respiratory and chronic disease management.

Citations