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Catalog Number:
38150
CAS Number:
50-24-8
Prednisolone
Purity:
97 - 103% (Assay on dried basis)
Synonym(s):
11ß,17a,21-Trihydroxypregna-1,4-diene-3,20-dione, 1,4-Pregnadiene-11b,17a,21-triol-3,20-dione
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Product Information

Prednisolone is a synthetic glucocorticoid with potent anti-inflammatory and immunosuppressive properties, widely utilized in various medical applications. This compound is particularly effective in treating conditions such as asthma, allergies, and autoimmune diseases due to its ability to modulate the immune response and reduce inflammation. Prednisolone is also employed in the management of certain cancers and as part of hormone replacement therapy, showcasing its versatility in therapeutic settings. Its unique structure allows for enhanced bioavailability and a favorable pharmacokinetic profile, making it a preferred choice among healthcare professionals.

In addition to its clinical applications, Prednisolone is of interest in research settings, where it is used to study the mechanisms of inflammation and immune response. Its effectiveness in reducing symptoms and improving quality of life for patients makes it a crucial compound in both pharmaceutical and research domains. With its well-established safety profile and efficacy, Prednisolone continues to be a vital tool in modern medicine.

Synonyms
11ß,17a,21-Trihydroxypregna-1,4-diene-3,20-dione, 1,4-Pregnadiene-11b,17a,21-triol-3,20-dione
CAS Number
50-24-8
Purity
97 - 103% (Assay on dried basis)
Molecular Formula
C21H28O5
Molecular Weight
360.45
MDL Number
MFCD00003649
PubChem ID
4894
Melting Point
234 - 236 °C (Lit.)
Appearance
Almost white crystalline powder
Optical Rotation
[a]D20 = 96 - 102 °
Conditions
Store at 2 - 8 °C
General Information
Synonyms
11ß,17a,21-Trihydroxypregna-1,4-diene-3,20-dione, 1,4-Pregnadiene-11b,17a,21-triol-3,20-dione
CAS Number
50-24-8
Purity
97 - 103% (Assay on dried basis)
Molecular Formula
C21H28O5
Molecular Weight
360.45
MDL Number
MFCD00003649
PubChem ID
4894
Melting Point
234 - 236 °C (Lit.)
Appearance
Almost white crystalline powder
Optical Rotation
[a]D20 = 96 - 102 °
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Prednisolone is widely utilized in research focused on:

  • Anti-inflammatory Treatments: Commonly used in the treatment of conditions like asthma, arthritis, and allergies, it helps reduce inflammation and improve patient comfort.
  • Autoimmune Disorders: Effective in managing diseases such as lupus and multiple sclerosis, it modulates the immune response, providing relief from symptoms.
  • Organ Transplantation: Plays a crucial role in preventing organ rejection by suppressing the immune system, ensuring better transplant success rates.
  • Dermatological Applications: Used in topical formulations for skin conditions like eczema and psoriasis, it helps alleviate redness and itching.
  • Research in Cancer Therapy: Investigated for its potential to enhance the effectiveness of certain chemotherapy regimens, offering a supportive role in cancer treatment.

Citations