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Catalog Number:
38148
CAS Number:
6054-98-4
Olsalazine sodium
Purity:
98.5 - 101.5% (HPLC)
Synonym(s):
5,5'-Azobis(2-hydroxybenzoic acid sodium salt), 4,4'-Dihydroxyazobenzene-3,3'-dicarboxylic acid disodium salt
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Product Information

Olsalazine sodium is a unique compound primarily utilized in the treatment of inflammatory bowel diseases, particularly ulcerative colitis. This sodium salt of olsalazine is known for its anti-inflammatory properties, making it a valuable therapeutic agent in clinical settings. Its mechanism of action involves the release of 5-aminosalicylic acid (5-ASA) in the colon, which helps to reduce inflammation and promote healing of the intestinal lining. Olsalazine sodium is often favored for its targeted delivery system, ensuring that the active ingredient is released where it is most needed, thus enhancing its efficacy compared to other treatments.

In addition to its medicinal applications, olsalazine sodium is also of interest in research settings, where it is studied for its potential effects on gut microbiota and overall digestive health. Researchers are exploring its role in modulating inflammatory responses, which could lead to new insights in gastrointestinal therapies. With its proven benefits and ongoing research, olsalazine sodium stands out as a significant compound for both therapeutic and investigative purposes.

Synonyms
5,5'-Azobis(2-hydroxybenzoic acid sodium salt), 4,4'-Dihydroxyazobenzene-3,3'-dicarboxylic acid disodium salt
CAS Number
6054-98-4
Purity
98.5 - 101.5% (HPLC)
Molecular Formula
C14H8N2Na2O6
Molecular Weight
346.21
MDL Number
MFCD00013300
PubChem ID
135413505
Melting Point
294 °C (dec.)
Appearance
Yellow to dark yellow crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5,5'-Azobis(2-hydroxybenzoic acid sodium salt), 4,4'-Dihydroxyazobenzene-3,3'-dicarboxylic acid disodium salt
CAS Number
6054-98-4
Purity
98.5 - 101.5% (HPLC)
Molecular Formula
C14H8N2Na2O6
Molecular Weight
346.21
MDL Number
MFCD00013300
PubChem ID
135413505
Melting Point
294 °C (dec.)
Appearance
Yellow to dark yellow crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Olsalazine sodium is widely utilized in research focused on:

  • Inflammatory Bowel Disease Treatment: Primarily used in the management of ulcerative colitis, it helps reduce inflammation and maintain remission in patients.
  • Pharmaceutical Formulations: Serves as an active ingredient in various oral medications, providing a targeted approach to gastrointestinal disorders.
  • Research on Drug Delivery Systems: Its properties are explored in developing innovative drug delivery methods, enhancing the bioavailability of therapeutic agents.
  • Analytical Chemistry: Used in laboratory settings to study the stability and degradation of pharmaceutical compounds, ensuring safety and efficacy in drug development.
  • Clinical Trials: Involved in clinical research to assess its effectiveness and safety, contributing to evidence-based medicine and improving treatment protocols.

Citations