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Catalog Number:
38147
CAS Number:
144689-63-4
Olmesartan medoxomil
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
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$145.52 /1G
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Product Information

Olmesartan medoxomil is a potent angiotensin II receptor antagonist, primarily utilized in the treatment of hypertension. This compound is recognized for its ability to effectively lower blood pressure by inhibiting the action of angiotensin II, a hormone that constricts blood vessels. Its unique structure allows for enhanced bioavailability and a prolonged duration of action, making it a preferred choice among healthcare professionals. Olmesartan medoxomil is often prescribed in combination with other antihypertensive agents, providing a synergistic effect that can lead to improved patient outcomes.

In addition to its primary use in managing high blood pressure, Olmesartan medoxomil has shown potential in the treatment of heart failure and chronic kidney disease, where blood pressure control is crucial. Its favorable side effect profile and efficacy make it a valuable option in clinical settings. Researchers are also exploring its applications in other cardiovascular conditions, highlighting its versatility and importance in modern medicine. With its established track record, Olmesartan medoxomil continues to be a significant player in the pharmaceutical landscape.

Synonyms
4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
CAS Number
144689-63-4
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C29H30N6O6
Molecular Weight
558.6
MDL Number
MFCD00944911
PubChem ID
130881
Melting Point
180 °C (dec.)
Appearance
White to light yellow powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
CAS Number
144689-63-4
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C29H30N6O6
Molecular Weight
558.6
MDL Number
MFCD00944911
PubChem ID
130881
Melting Point
180 °C (dec.)
Appearance
White to light yellow powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Olmesartan medoxomil is widely utilized in research focused on:

  • Hypertension Management: This compound is primarily used in the treatment of high blood pressure, helping to reduce the risk of heart disease and stroke. Its effectiveness in lowering blood pressure makes it a preferred choice among healthcare providers.
  • Cardiovascular Research: Researchers study its effects on cardiovascular health, examining how it can improve outcomes in patients with heart-related conditions. Clinical trials often explore its long-term benefits and safety profile.
  • Combination Therapies: Olmesartan medoxomil is frequently used in combination with other antihypertensive agents, enhancing overall efficacy and patient compliance. This approach allows for tailored treatment plans based on individual patient needs.
  • Renal Protection Studies: It is also investigated for its protective effects on kidney function, particularly in patients with diabetes or chronic kidney disease. This application is crucial for preventing progression to more severe renal issues.
  • Pharmaceutical Development: The compound serves as a model for developing new antihypertensive medications, inspiring research into similar compounds with improved efficacy and fewer side effects.

Citations