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Catalog Number:
38146
CAS Number:
144689-24-7
Olmesartan
Purity:
≥ 98% (HPLC)
Synonym(s):
4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid, Olmesartan acid
Documents
$174.96 /100MG
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Product Information

Olmesartan is a potent angiotensin II receptor antagonist primarily used in the treatment of hypertension. This compound works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby promoting vasodilation and lowering blood pressure. Its unique structure, featuring a tetrazole ring, enhances its binding affinity and selectivity for the angiotensin receptor, making it a preferred choice for managing high blood pressure in patients who may not respond adequately to other antihypertensive agents.

In addition to its primary use in hypertension, Olmesartan has shown potential benefits in reducing the risk of cardiovascular events and improving renal outcomes in patients with diabetes. Its favorable pharmacokinetic profile allows for once-daily dosing, improving patient compliance. Researchers and healthcare professionals appreciate Olmesartan for its efficacy and safety profile, making it a valuable addition to the therapeutic arsenal against cardiovascular diseases.

Synonyms
4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid, Olmesartan acid
CAS Number
144689-24-7
Purity
≥ 98% (HPLC)
Molecular Formula
C24H26N6O3
Molecular Weight
446.51
MDL Number
MFCD00914967
PubChem ID
158781
Melting Point
177 °C (dec.)
Appearance
White to light yellow powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid, Olmesartan acid
CAS Number
144689-24-7
Purity
≥ 98% (HPLC)
Molecular Formula
C24H26N6O3
Molecular Weight
446.51
MDL Number
MFCD00914967
PubChem ID
158781
Melting Point
177 °C (dec.)
Appearance
White to light yellow powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Olmesartan is widely utilized in research focused on:

  • Hypertension Management: It is primarily used as an antihypertensive agent to treat high blood pressure, helping to reduce the risk of heart disease and stroke.
  • Cardiovascular Research: Researchers explore its effects on cardiovascular health, studying how it can improve heart function and reduce complications associated with hypertension.
  • Diabetes-Related Studies: Olmesartan is investigated for its potential benefits in diabetic patients, particularly in protecting kidney function and reducing the risk of diabetic nephropathy.
  • Combination Therapies: It is often used in combination with other antihypertensive medications, allowing for more effective blood pressure control with potentially fewer side effects.
  • Pharmacological Research: Ongoing studies focus on its mechanism of action and long-term effects, contributing to the development of new treatment protocols for hypertension and related conditions.

Citations