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Catalog Number:
38139
CAS Number:
16773-42-5
Ornidazole
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
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Product Information

Ornidazole is a potent nitroimidazole derivative widely recognized for its antimicrobial properties, particularly in the treatment of protozoal infections such as amoebiasis and giardiasis. This compound is characterized by its ability to disrupt DNA synthesis in anaerobic bacteria and protozoa, making it an effective therapeutic agent in both human and veterinary medicine. Its unique structure, featuring a nitro group and an imidazole ring, enhances its bioactivity and allows for effective penetration into microbial cells, providing a significant advantage over other similar compounds.

In addition to its medical applications, Ornidazole is also utilized in research settings, particularly in studies focused on microbial resistance and the development of new antimicrobial agents. Its effectiveness against a broad spectrum of pathogens, coupled with a favorable safety profile, positions Ornidazole as a valuable tool for healthcare professionals and researchers alike. With its proven efficacy and versatility, Ornidazole continues to play a crucial role in combating infectious diseases and advancing microbiological research.

Synonyms
1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
CAS Number
16773-42-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C7H10ClN3O3
Molecular Weight
219.63
MDL Number
MFCD00057960
PubChem ID
28061
Melting Point
90 - 94 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(3-Chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole
CAS Number
16773-42-5
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C7H10ClN3O3
Molecular Weight
219.63
MDL Number
MFCD00057960
PubChem ID
28061
Melting Point
90 - 94 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ornidazole is widely utilized in research focused on:

  • Antimicrobial Treatments: It is primarily used in the treatment of various infections, particularly those caused by anaerobic bacteria and protozoa, making it valuable in both clinical and veterinary settings.
  • Pharmaceutical Development: Researchers leverage its properties to develop new formulations and dosage forms, enhancing the efficacy of treatments for conditions like amoebiasis and giardiasis.
  • Clinical Trials: Ornidazole is frequently involved in clinical studies assessing its effectiveness against resistant strains of pathogens, providing critical data for healthcare advancements.
  • Combination Therapies: It is often used in combination with other antibiotics to broaden the spectrum of activity, which is particularly beneficial in treating polymicrobial infections.
  • Research on Drug Resistance: The compound serves as a model in studies investigating mechanisms of drug resistance, helping to inform strategies for overcoming challenges in infectious disease management.

Citations