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Nocodazole
Nocodazole is widely utilized in research focused on:
- Cell Cycle Studies: This compound is a potent microtubule inhibitor, making it invaluable for researchers studying the cell cycle and mitosis. By disrupting microtubule dynamics, it helps in understanding cellular processes and the effects of various drugs on cell division.
- Cancer Research: Nocodazole is frequently used in cancer studies to investigate the mechanisms of tumor growth and metastasis. Its ability to halt cell division allows scientists to explore potential therapeutic strategies for targeting cancer cells.
- Neuroscience: In neuroscience, nocodazole is employed to study neuronal transport mechanisms. By inhibiting microtubule function, researchers can gain insights into neurodegenerative diseases and the role of cytoskeletal dynamics in neuronal health.
- Drug Development: Pharmaceutical companies utilize nocodazole in the early stages of drug development to screen for compounds that can effectively target microtubule dynamics, leading to the discovery of new anti-cancer agents.
- Genetic Studies: It is also applied in genetic research to synchronize cells at specific phases of the cell cycle, allowing for more accurate analysis of gene expression and function during different stages of cellular activity.
General Information
Properties
Safety and Regulations
Applications
Nocodazole is widely utilized in research focused on:
- Cell Cycle Studies: This compound is a potent microtubule inhibitor, making it invaluable for researchers studying the cell cycle and mitosis. By disrupting microtubule dynamics, it helps in understanding cellular processes and the effects of various drugs on cell division.
- Cancer Research: Nocodazole is frequently used in cancer studies to investigate the mechanisms of tumor growth and metastasis. Its ability to halt cell division allows scientists to explore potential therapeutic strategies for targeting cancer cells.
- Neuroscience: In neuroscience, nocodazole is employed to study neuronal transport mechanisms. By inhibiting microtubule function, researchers can gain insights into neurodegenerative diseases and the role of cytoskeletal dynamics in neuronal health.
- Drug Development: Pharmaceutical companies utilize nocodazole in the early stages of drug development to screen for compounds that can effectively target microtubule dynamics, leading to the discovery of new anti-cancer agents.
- Genetic Studies: It is also applied in genetic research to synchronize cells at specific phases of the cell cycle, allowing for more accurate analysis of gene expression and function during different stages of cellular activity.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.