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Catalog Number:
38105
CAS Number:
78281-72-8
Nepafenac
Purity:
98.0 - 101.5% (Assay)
Synonym(s):
2-Amino-3-benzoylbenzeneacetamide, 2-(2-Amino-3-benzoylphenyl)acetamide
Documents
$173.66 /200MG
Pack Size Availability Price
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Product Information

Nepafenac is a potent non-steroidal anti-inflammatory drug (NSAID) primarily used in ophthalmology for the treatment of pain and inflammation associated with cataract surgery. Its unique mechanism of action involves the inhibition of cyclooxygenase enzymes, which play a crucial role in the inflammatory response. This compound is particularly valued for its ability to penetrate ocular tissues effectively, providing rapid relief from postoperative discomfort. Researchers and healthcare professionals appreciate Nepafenac for its targeted action and minimal systemic absorption, making it a safer choice for patients.

In addition to its primary application in eye care, Nepafenac has shown potential in various research settings, including studies on ocular inflammation and pain management. Its formulation as an eye drop allows for easy administration and enhances patient compliance. The compound's efficacy in reducing inflammation without the side effects commonly associated with traditional NSAIDs makes it a preferred option in clinical settings. With ongoing research, Nepafenac continues to hold promise for expanding its applications in other therapeutic areas.

Synonyms
2-Amino-3-benzoylbenzeneacetamide, 2-(2-Amino-3-benzoylphenyl)acetamide
CAS Number
78281-72-8
Purity
98.0 - 101.5% (Assay)
Molecular Formula
C15H14N2O2
Molecular Weight
254.29
MDL Number
MFCD08067732
PubChem ID
151075
Melting Point
182 - 186 °C (Lit.)
Appearance
Yellow or light yellow crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2-Amino-3-benzoylbenzeneacetamide, 2-(2-Amino-3-benzoylphenyl)acetamide
CAS Number
78281-72-8
Purity
98.0 - 101.5% (Assay)
Molecular Formula
C15H14N2O2
Molecular Weight
254.29
MDL Number
MFCD08067732
PubChem ID
151075
Melting Point
182 - 186 °C (Lit.)
Appearance
Yellow or light yellow crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nepafenac is widely utilized in research focused on:

  • Ophthalmic Solutions: Primarily used in eye drops for the treatment of pain and inflammation following cataract surgery, providing quick relief and improving patient comfort.
  • Anti-inflammatory Research: Investigated for its efficacy in reducing inflammation in various conditions, making it valuable for researchers studying pain management and anti-inflammatory therapies.
  • Pharmaceutical Development: Serves as a model compound in the development of new non-steroidal anti-inflammatory drugs (NSAIDs), helping to enhance formulations and delivery methods.
  • Clinical Trials: Frequently involved in clinical studies assessing its effectiveness and safety, offering insights into patient responses and potential side effects.
  • Combination Therapies: Explored in conjunction with other medications to enhance therapeutic effects, particularly in managing post-operative pain, showcasing its versatility in treatment plans.

Citations