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Catalog Number:
38102
CAS Number:
105816-04-4
Nateglinide
Purity:
≥ 98% (HPLC)
Synonym(s):
N-[(trans-4-isopropylcyclohexyl)carbonyl]-D-phenylalanine, Starsis
Documents
$142.81 /500MG
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Product Information

Nateglinide is a potent and selective D-phenylalanine derivative, primarily utilized in the management of type 2 diabetes mellitus. This compound functions as a rapid-acting insulin secretagogue, stimulating the pancreas to release insulin in response to meals, thereby helping to control postprandial blood glucose levels. Its unique mechanism of action allows for a quick onset of effect, making it particularly beneficial for patients who experience spikes in blood sugar after eating. Nateglinide is often prescribed in conjunction with dietary modifications and exercise to optimize glycemic control.

In addition to its primary use in diabetes management, Nateglinide has shown potential in research settings for exploring novel therapeutic approaches in metabolic disorders. Its favorable pharmacokinetic profile, including a short half-life, allows for flexible dosing, making it an attractive option for personalized diabetes care. Researchers and healthcare professionals appreciate Nateglinide for its ability to provide targeted glucose control, enhancing patient outcomes and improving overall quality of life.

Synonyms
N-[(trans-4-isopropylcyclohexyl)carbonyl]-D-phenylalanine, Starsis
CAS Number
105816-04-4
Purity
≥ 98% (HPLC)
Molecular Formula
C19H27NO3
Molecular Weight
317.43
MDL Number
MFCD00875706
PubChem ID
4443
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -36 to -40 ° (C=1, 0.1 mol/L NaOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-[(trans-4-isopropylcyclohexyl)carbonyl]-D-phenylalanine, Starsis
CAS Number
105816-04-4
Purity
≥ 98% (HPLC)
Molecular Formula
C19H27NO3
Molecular Weight
317.43
MDL Number
MFCD00875706
PubChem ID
4443
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -36 to -40 ° (C=1, 0.1 mol/L NaOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nateglinide is widely utilized in research focused on:

  • Diabetes Management: Primarily used as an oral medication for type 2 diabetes, it helps control blood sugar levels by stimulating insulin release from the pancreas after meals.
  • Pharmaceutical Development: Researchers are exploring its potential in combination therapies to enhance glycemic control, making it a valuable compound in drug formulation studies.
  • Clinical Trials: Nateglinide is often included in clinical trials to assess its efficacy and safety, providing critical data for diabetes treatment advancements.
  • Patient Compliance: Its rapid action and short duration of effect make it easier for patients to manage their blood sugar levels, addressing the challenge of adherence to medication regimens.
  • Comparative Studies: It serves as a benchmark in studies comparing new antidiabetic agents, allowing researchers to evaluate the effectiveness of newer drugs against established treatments.

Citations