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Catalog Number:
38099
CAS Number:
66085-59-4
Nimodipine
Purity:
≥ 98% (HPLC)
Synonym(s):
isopropyl 2-Methoxyethyl1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid 2-methoxyethyl 1-methylethyl ester
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Product Information

Nimodipine is a potent calcium channel blocker primarily used in the medical field for its ability to improve cerebral blood flow. This compound is particularly effective in the treatment of subarachnoid hemorrhage, where it helps prevent vasospasm and enhances neurological outcomes. Its unique structure allows for selective action on cerebral blood vessels, making it a valuable asset in neuroprotective therapies. Researchers and healthcare professionals appreciate Nimodipine for its efficacy in managing conditions related to impaired blood flow, and its application extends to studies investigating its potential benefits in various neurological disorders.

In addition to its clinical applications, Nimodipine is also of interest in pharmaceutical research for developing novel formulations aimed at enhancing bioavailability and therapeutic efficacy. Its favorable pharmacokinetic profile and ability to cross the blood-brain barrier make it a candidate for further exploration in drug delivery systems. As a result, Nimodipine stands out not only for its established medical uses but also for its potential in advancing therapeutic strategies in neurology.

Synonyms
isopropyl 2-Methoxyethyl1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid 2-methoxyethyl 1-methylethyl ester
CAS Number
66085-59-4
Purity
≥ 98% (HPLC)
Molecular Formula
C21H26N2O7
Molecular Weight
418.45
MDL Number
MFCD00153848
PubChem ID
4497
Melting Point
124 - 128 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
isopropyl 2-Methoxyethyl1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate, 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacid 2-methoxyethyl 1-methylethyl ester
CAS Number
66085-59-4
Purity
≥ 98% (HPLC)
Molecular Formula
C21H26N2O7
Molecular Weight
418.45
MDL Number
MFCD00153848
PubChem ID
4497
Melting Point
124 - 128 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nimodipine is widely utilized in research focused on:

  • Treatment of Subarachnoid Hemorrhage: Nimodipine is primarily used in clinical settings to improve outcomes in patients who have suffered a subarachnoid hemorrhage, helping to prevent complications such as vasospasm.
  • Neuroprotection: Researchers explore its neuroprotective properties, which may benefit conditions like stroke and traumatic brain injury by improving blood flow to the brain.
  • Cardiovascular Research: The compound is studied for its effects on vascular smooth muscle, making it relevant in research on hypertension and other cardiovascular diseases.
  • Pharmaceutical Development: Nimodipine serves as a model compound in drug formulation studies, particularly in the development of sustained-release formulations due to its unique pharmacokinetic profile.
  • Investigating Calcium Channel Blockers: It is commonly used in studies examining the role of calcium channel blockers in various physiological and pathological processes, providing insights into their therapeutic potential.

Citations