Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
38088
CAS Number:
53-19-0
Mitotane
Purity:
≥ 98% (GC)
Synonym(s):
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, o,p'-DDD
Documents
$116.67 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Mitotane is a potent pharmaceutical compound primarily utilized in the treatment of adrenocortical carcinoma, a rare form of cancer affecting the adrenal glands. With its unique structure, Mitotane exhibits selective cytotoxicity towards adrenal cortex cells, making it an essential agent in oncology. Its mechanism of action involves the disruption of adrenal steroidogenesis, leading to decreased cortisol production, which is crucial for managing hypercortisolism in patients. Researchers and healthcare professionals value Mitotane for its ability to improve patient outcomes in cases where conventional therapies may fall short.

In addition to its primary use in cancer treatment, Mitotane has shown potential in research settings, particularly in studies focused on adrenal function and steroid metabolism. Its unique properties allow for targeted therapeutic strategies, providing a significant advantage over other compounds in similar applications. As a result, Mitotane is not only a critical component in the clinical management of specific cancers but also a valuable tool for advancing scientific understanding in endocrinology and oncology.

Synonyms
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, o,p'-DDD
CAS Number
53-19-0
Purity
≥ 98% (GC)
Molecular Formula
C14H10Cl4
Molecular Weight
320.03
MDL Number
MFCD00000850
PubChem ID
4211
Melting Point
76 - 80 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, o,p'-DDD
CAS Number
53-19-0
Purity
≥ 98% (GC)
Molecular Formula
C14H10Cl4
Molecular Weight
320.03
MDL Number
MFCD00000850
PubChem ID
4211
Melting Point
76 - 80 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mitotane is widely utilized in research focused on:

  • Adrenocortical Carcinoma Treatment: It is primarily used in the treatment of adrenal gland cancer, helping to reduce tumor size and manage symptoms effectively.
  • Hormonal Regulation Studies: Researchers use Mitotane to study its effects on hormone production, particularly cortisol, providing insights into adrenal function and disorders.
  • Drug Interaction Research: It serves as a model compound in pharmacology to investigate interactions with other medications, enhancing understanding of drug metabolism and safety profiles.
  • Animal Models in Oncology: Mitotane is employed in preclinical studies using animal models to evaluate new therapies for adrenal tumors, aiding in the development of innovative treatments.
  • Clinical Trials: It plays a crucial role in clinical trials aimed at improving treatment protocols for adrenal cancer, offering potential benefits over traditional therapies.

Citations