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Catalog Number:
38084
CAS Number:
70476-82-3
Mitoxantrone dihydrochloride
Purity:
≥ 97% (HPLC)
Synonym(s):
1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinonedihydrochloride, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dionedihydrochloride
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$101.45 /25MG
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Product Information

Mitoxantrone dihydrochloride is a potent anthracenedione derivative primarily utilized in the treatment of various cancers, including leukemia and prostate cancer. This compound exhibits unique properties that enhance its efficacy as a chemotherapeutic agent, making it a valuable choice in oncology. Its mechanism of action involves intercalating DNA, which disrupts the replication process and ultimately leads to cell death. Researchers and healthcare professionals appreciate Mitoxantrone dihydrochloride for its ability to target rapidly dividing cells, providing a strategic advantage in cancer treatment protocols.

In addition to its primary applications in cancer therapy, Mitoxantrone dihydrochloride has shown promise in treating multiple sclerosis, where it helps to reduce the frequency of relapses. Its dual functionality in oncology and neurology underscores its versatility and relevance in modern medicine. With a favorable safety profile compared to other chemotherapeutics, this compound is an essential tool for healthcare providers aiming to improve patient outcomes in challenging therapeutic areas.

Synonyms
1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinonedihydrochloride, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dionedihydrochloride
CAS Number
70476-82-3
Purity
≥ 97% (HPLC)
Molecular Formula
C22H28N4O6·2HCl
Molecular Weight
517.4
MDL Number
MFCD00242943
PubChem ID
51082
Melting Point
267 °C (dec.)
Appearance
Dark green to dark purple to black powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinonedihydrochloride, 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthracene-9,10-dionedihydrochloride
CAS Number
70476-82-3
Purity
≥ 97% (HPLC)
Molecular Formula
C22H28N4O6·2HCl
Molecular Weight
517.4
MDL Number
MFCD00242943
PubChem ID
51082
Melting Point
267 °C (dec.)
Appearance
Dark green to dark purple to black powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mitoxantrone dihydrochloride is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily used in oncology as a chemotherapy agent for treating various types of cancer, including breast cancer and leukemia. Its ability to intercalate DNA helps inhibit cancer cell growth.
  • Multiple Sclerosis Therapy: It is also prescribed for patients with multiple sclerosis, providing benefits by reducing the frequency of relapses and slowing disease progression.
  • Research in Drug Development: Scientists use this compound in laboratory settings to study its effects and mechanisms, aiding in the development of new cancer therapies and improving existing treatment protocols.
  • Combination Therapy: Mitoxantrone dihydrochloride is often used in combination with other chemotherapeutic agents, enhancing treatment efficacy while potentially reducing side effects compared to monotherapy.
  • Targeted Drug Delivery Systems: Researchers are exploring its use in novel drug delivery systems, which can improve the targeting of cancer cells while minimizing damage to healthy tissues, thus increasing treatment safety and effectiveness.

Citations