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Catalog Number:
38075
CAS Number:
1104-22-9
Meclizine dihydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
1-(4-Chlorobenzhydryl)-4-(3-methylbenzyl)piperazinedihydrochloride
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Product Information

Meclizine dihydrochloride is a well-established antihistamine primarily used for the prevention and treatment of motion sickness and vertigo. This compound is recognized for its ability to effectively reduce nausea and dizziness associated with these conditions, making it a valuable asset in both clinical and over-the-counter applications. Its unique structure allows for a prolonged duration of action, providing relief for patients during travel or in situations that may induce motion-related discomfort.

In addition to its primary use in treating motion sickness, Meclizine dihydrochloride has been explored for its potential benefits in managing symptoms of vestibular disorders and as an adjunct therapy in certain neurological conditions. Researchers appreciate its favorable safety profile and efficacy, which make it a preferred choice in various therapeutic settings. The compound's versatility and effectiveness in alleviating discomfort highlight its significance in both pharmaceutical formulations and clinical practice.

Synonyms
1-(4-Chlorobenzhydryl)-4-(3-methylbenzyl)piperazinedihydrochloride
CAS Number
1104-22-9
Purity
≥ 98% (HPLC)
Molecular Formula
C25H27ClN2·2HCl
Molecular Weight
463.87
MDL Number
MFCD00058199
PubChem ID
64713
Melting Point
210 - 214 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(4-Chlorobenzhydryl)-4-(3-methylbenzyl)piperazinedihydrochloride
CAS Number
1104-22-9
Purity
≥ 98% (HPLC)
Molecular Formula
C25H27ClN2·2HCl
Molecular Weight
463.87
MDL Number
MFCD00058199
PubChem ID
64713
Melting Point
210 - 214 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Meclizine dihydrochloride is widely utilized in research focused on:

  • Motion Sickness Relief: Commonly used in over-the-counter medications to prevent and treat motion sickness, making it essential for travelers and those prone to nausea during movement.
  • Vertigo Management: Employed in clinical settings to alleviate symptoms of vertigo, providing relief for patients suffering from balance disorders.
  • Antihistamine Applications: Functions as an antihistamine, offering benefits in allergy treatments by reducing symptoms such as itching, sneezing, and runny nose.
  • Research in Neurology: Investigated in studies related to neurological conditions, where its effects on the central nervous system can provide insights into treatment options for various disorders.
  • Veterinary Medicine: Used in veterinary practices to manage motion sickness in pets, ensuring a more comfortable travel experience for animals and their owners.

Citations