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Catalog Number:
38059
CAS Number:
25717-80-0
Molsidomine
Purity:
≥ 98% (Assay by titration, HPLC)
Synonym(s):
N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine
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$111.17 /1G
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Product Information

Molsidomine is a potent vasodilator primarily used in the management of angina pectoris and other cardiovascular conditions. This compound works by releasing nitric oxide, which relaxes blood vessels and improves blood flow, making it a valuable option for patients with ischemic heart disease. Its unique mechanism of action allows for a sustained therapeutic effect, distinguishing it from traditional nitrates. Molsidomine is also being explored for its potential applications in treating pulmonary hypertension and heart failure, showcasing its versatility in cardiovascular therapy.

In research settings, Molsidomine's ability to modulate vascular tone and improve endothelial function makes it a subject of interest for studies on cardiovascular health and disease. Its favorable pharmacokinetic profile, including oral bioavailability and a relatively quick onset of action, enhances its appeal for both clinical and research applications. As a reliable choice for enhancing cardiovascular health, Molsidomine stands out for its efficacy and safety in various therapeutic contexts.

Synonyms
N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine
CAS Number
25717-80-0
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C9H14N4O4
Molecular Weight
242.24
MDL Number
MFCD00869301
PubChem ID
4238
Melting Point
139 - 143 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine
CAS Number
25717-80-0
Purity
≥ 98% (Assay by titration, HPLC)
Molecular Formula
C9H14N4O4
Molecular Weight
242.24
MDL Number
MFCD00869301
PubChem ID
4238
Melting Point
139 - 143 °C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Molsidomine is widely utilized in research focused on:

  • Cardiovascular Medicine: Molsidomine is primarily used as a vasodilator to treat angina pectoris. It helps improve blood flow and reduce chest pain, making it a valuable option for patients with heart conditions.
  • Pharmacological Studies: Researchers use molsidomine to study its effects on nitric oxide pathways, which are crucial for understanding various cardiovascular diseases and developing new treatments.
  • Combination Therapies: In clinical settings, molsidomine is often combined with other medications to enhance therapeutic effects, particularly in managing chronic heart failure and hypertension.
  • Research on Tolerance Mechanisms: Molsidomine is utilized in studies exploring tolerance development to nitrates, providing insights that can lead to improved treatment protocols for patients requiring long-term therapy.
  • Innovative Drug Formulations: The compound is being investigated for its potential in novel drug delivery systems, which could enhance the efficacy and reduce side effects of existing cardiovascular medications.

Citations