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Catalog Number:
38050
CAS Number:
31431-39-7
Mebendazole
Grade:
Meets USP Specification
Purity:
98 - 102% (Assay on dried basis)
Synonym(s):
Methyl [5-(Benzoyl)benzimidazol-2-yl]carbamate
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Product Information

Mebendazole is a broad-spectrum anthelmintic agent widely used in the treatment of parasitic worm infections, particularly in humans and animals. This compound is effective against a variety of intestinal parasites, including roundworms, hookworms, and whipworms, making it a vital tool in both veterinary and human medicine. Its mechanism of action involves inhibiting the polymerization of tubulin, which disrupts the cytoskeleton of the parasites, ultimately leading to their death. Mebendazole is often administered in a chewable tablet form, enhancing patient compliance, especially in pediatric cases.

In addition to its primary use in treating helminthic infections, Mebendazole has shown potential in research settings for its anti-cancer properties, particularly in targeting certain types of tumors. Its low toxicity profile and ability to be used in combination with other therapies make it an attractive candidate for further investigation in oncology. With its proven efficacy and expanding applications, Mebendazole remains a crucial compound in both therapeutic and research contexts.

Synonyms
Methyl [5-(Benzoyl)benzimidazol-2-yl]carbamate
CAS Number
31431-39-7
Purity
98 - 102% (Assay on dried basis)
Grade
Meets USP Specification
Molecular Formula
C16H13N3O3
Molecular Weight
295.3
MDL Number
MFCD00057872
PubChem ID
4030
Melting Point
286 - 288 °C (Lit.)
Appearance
White to slightly yellow powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Methyl [5-(Benzoyl)benzimidazol-2-yl]carbamate
CAS Number
31431-39-7
Purity
98 - 102% (Assay on dried basis)
Grade
Meets USP Specification
Molecular Formula
C16H13N3O3
Molecular Weight
295.3
MDL Number
MFCD00057872
PubChem ID
4030
Melting Point
286 - 288 °C (Lit.)
Appearance
White to slightly yellow powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mebendazole is widely utilized in research focused on:

  • Antiparasitic Treatments: Primarily used to treat parasitic infections such as roundworm and hookworm, making it essential in both human and veterinary medicine.
  • Pharmaceutical Formulations: Incorporated into various drug formulations due to its effectiveness and low toxicity, enhancing patient compliance and treatment outcomes.
  • Research on Drug Resistance: A valuable compound in studies investigating drug resistance in parasites, helping researchers develop more effective treatments.
  • Veterinary Medicine: Extensively used in the livestock industry to control parasitic infections, thereby improving animal health and productivity.
  • Potential Anticancer Properties: Emerging research suggests it may have applications in cancer treatment, providing a new avenue for therapeutic exploration.

Citations