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Catalog Number:
38037
CAS Number:
133073-73-1
Methotrexate hydrate
Purity:
≥ 98% (HPLC)
Synonym(s):
(+)-Amethopterin hydrate, 4-Amino-10-methylfolic acid hydrate
Hazmat
Documents
$234.85 /1G
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Product Information
Synonyms
(+)-Amethopterin hydrate, 4-Amino-10-methylfolic acid hydrate
CAS Number
133073-73-1
Purity
≥ 98% (HPLC)
Molecular Formula
C20H22N8O5·xH2O
Molecular Weight
0
MDL Number
MFCD00150847
PubChem ID
24207740
Melting Point
200 - 205 °C (Lit.)
Appearance
Light yellow to brown powder to crystal
Optical Rotation
[a]D20 = 18 - 23 ° (C=0.1 in 1mol/L NaOH sol.)(calcd.on anh.substance)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(+)-Amethopterin hydrate, 4-Amino-10-methylfolic acid hydrate
CAS Number
133073-73-1
Purity
≥ 98% (HPLC)
Molecular Formula
C20H22N8O5·xH2O
Molecular Weight
0
MDL Number
MFCD00150847
PubChem ID
24207740
Melting Point
200 - 205 °C (Lit.)
Appearance
Light yellow to brown powder to crystal
Optical Rotation
[a]D20 = 18 - 23 ° (C=0.1 in 1mol/L NaOH sol.)(calcd.on anh.substance)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methotrexate hydrate is widely utilized in research focused on:

  • Cancer Treatment: This compound is a cornerstone in chemotherapy regimens for various cancers, including leukemia and lymphoma, by inhibiting cell growth and division.
  • Autoimmune Disorders: It is effective in treating conditions like rheumatoid arthritis and psoriasis, helping to reduce inflammation and immune system activity.
  • Fertility Treatments: Researchers explore its role in fertility, particularly in managing ectopic pregnancies and in certain assisted reproductive technologies.
  • Drug Development: Methotrexate hydrate serves as a model compound in pharmaceutical research, aiding in the development of new drugs targeting similar pathways.
  • Biochemical Studies: It is used in laboratory settings to study folate metabolism and its implications in cellular processes, providing insights into various metabolic disorders.

Citations