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Catalog Number:
38013
CAS Number:
132866-11-6
Lercanidipine hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethylmethyl ester 3,5-pyridinedicarboxylic acid hydrochloride
Documents
$144.12 /200MG
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Product Information

Lercanidipine hydrochloride is a potent calcium channel blocker primarily utilized in the management of hypertension. This compound is recognized for its ability to selectively inhibit L-type calcium channels, leading to vasodilation and a subsequent reduction in blood pressure. Its unique structure allows for a prolonged action, making it an effective choice for once-daily dosing, which enhances patient compliance. Lercanidipine hydrochloride is particularly beneficial in treating patients with essential hypertension, as it not only lowers blood pressure but also improves overall cardiovascular health by reducing the workload on the heart.

In addition to its primary use in hypertension, Lercanidipine hydrochloride has shown promise in various research applications, including studies focused on cardiovascular diseases and metabolic disorders. Its favorable pharmacokinetic profile, including high bioavailability and minimal side effects, positions it as a preferred option compared to other calcium channel blockers. Researchers and healthcare professionals can leverage Lercanidipine hydrochloride for innovative therapeutic strategies, making it a valuable addition to any pharmaceutical portfolio.

Synonyms
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethylmethyl ester 3,5-pyridinedicarboxylic acid hydrochloride
CAS Number
132866-11-6
Purity
≥ 98% (HPLC)
Molecular Formula
C36H41N3O6·HCl
Molecular Weight
648.2
MDL Number
MFCD07773089
PubChem ID
157917
Melting Point
194 - 196 °C (dec.)
Appearance
Light orange to yellow to green powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethylmethyl ester 3,5-pyridinedicarboxylic acid hydrochloride
CAS Number
132866-11-6
Purity
≥ 98% (HPLC)
Molecular Formula
C36H41N3O6·HCl
Molecular Weight
648.2
MDL Number
MFCD07773089
PubChem ID
157917
Melting Point
194 - 196 °C (dec.)
Appearance
Light orange to yellow to green powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Lercanidipine hydrochloride is widely utilized in research focused on:

  • Cardiovascular Health: This compound is primarily used as an antihypertensive agent, helping to lower blood pressure in patients with hypertension. Its effectiveness in managing high blood pressure makes it a vital option for healthcare providers.
  • Pharmaceutical Development: Researchers are exploring its potential in combination therapies for cardiovascular diseases, enhancing treatment efficacy and patient outcomes.
  • Clinical Studies: It is frequently involved in clinical trials aimed at understanding its long-term effects on heart health, providing valuable data for future medical guidelines.
  • Formulation Research: The compound is studied for its solubility and bioavailability characteristics, which are crucial for developing effective oral medications that ensure better patient adherence.
  • Patient-Centric Approaches: Lercanidipine hydrochloride is appreciated for its once-daily dosing, which improves convenience for patients, making it easier to integrate into their daily routines compared to other antihypertensives that require multiple doses.

Citations