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Catalog Number:
38002
CAS Number:
112809-51-5
Letrozole
Purity:
≥ 98% (HPLC)
Synonym(s):
1-Bis(4-cyanophenyl)methyl-1,2,4-triazole, 4,4'-(1,2,4-Triazol-1-ylmethylene)dibenzonitrile
Documents
$264.60 /1G
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Product Information

Letrozole is a potent aromatase inhibitor primarily utilized in the treatment of hormone receptor-positive breast cancer in postmenopausal women. By effectively reducing estrogen production, Letrozole plays a crucial role in slowing the growth of certain types of breast tumors that require estrogen to thrive. Its unique mechanism of action makes it a preferred choice in adjuvant therapy, particularly for patients with early-stage breast cancer, as well as in advanced cases. Researchers and healthcare professionals appreciate Letrozole for its favorable side effect profile compared to other hormonal therapies, making it a valuable option in oncology.

In addition to its primary use in breast cancer treatment, Letrozole has shown promise in fertility treatments, particularly in women with polycystic ovary syndrome (PCOS) who are seeking to induce ovulation. Its ability to stimulate ovarian function while minimizing the risk of multiple pregnancies positions it as a beneficial alternative to traditional fertility medications. With ongoing research, Letrozole continues to demonstrate its versatility and effectiveness in various therapeutic areas, making it a significant compound in both oncology and reproductive health.

Synonyms
1-Bis(4-cyanophenyl)methyl-1,2,4-triazole, 4,4'-(1,2,4-Triazol-1-ylmethylene)dibenzonitrile
CAS Number
112809-51-5
Purity
≥ 98% (HPLC)
Molecular Formula
C17H11N5
Molecular Weight
285.31
MDL Number
MFCD00866241
PubChem ID
3902
Melting Point
183 - 187 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-Bis(4-cyanophenyl)methyl-1,2,4-triazole, 4,4'-(1,2,4-Triazol-1-ylmethylene)dibenzonitrile
CAS Number
112809-51-5
Purity
≥ 98% (HPLC)
Molecular Formula
C17H11N5
Molecular Weight
285.31
MDL Number
MFCD00866241
PubChem ID
3902
Melting Point
183 - 187 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Letrozole is widely utilized in research focused on:

  • Breast Cancer Treatment: Primarily used as an aromatase inhibitor in hormone receptor-positive breast cancer, helping to lower estrogen levels and slow tumor growth.
  • Fertility Treatments: Employed in ovulation induction for women with polycystic ovary syndrome (PCOS), offering a less invasive alternative to traditional fertility drugs.
  • Research on Hormonal Therapies: Used in studies to explore the effects of estrogen suppression on various cancers, providing insights into treatment efficacy and patient outcomes.
  • Endocrinology Studies: Helps researchers understand the role of hormones in metabolic processes, contributing to advancements in diabetes and obesity research.
  • Veterinary Medicine: Investigated for its potential in treating hormone-dependent conditions in animals, showcasing its versatility beyond human applications.

Citations