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Catalog Number:
38000
CAS Number:
101477-54-7
Lomerizine dihydrochloride
Purity:
≥ 98.5% (Assay on dry basis)
Synonym(s):
1-[Bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazinedihydrochloride
Documents
$40.00 /250MG
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Product Information

Lomerizine dihydrochloride is a potent compound recognized for its application in the treatment of migraine and other vascular headaches. This piperazine derivative exhibits unique pharmacological properties, making it a valuable asset in both clinical and research settings. Its ability to selectively inhibit calcium channels contributes to its efficacy in alleviating headache symptoms, providing relief for patients suffering from chronic migraines. Additionally, Lomerizine dihydrochloride has shown promise in studies related to neuroprotection, which may open avenues for further research in neurological disorders.

Researchers and industry professionals can benefit from Lomerizine dihydrochloride's versatility in formulation development, particularly in the pharmaceutical sector. Its favorable safety profile and targeted action make it an attractive candidate for innovative migraine therapies. Furthermore, the compound's unique structure allows for potential modifications that could enhance its therapeutic effects, positioning it as a leading choice for future drug development initiatives.

Synonyms
1-[Bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazinedihydrochloride
CAS Number
101477-54-7
Purity
≥ 98.5% (Assay on dry basis)
Molecular Formula
C27H30F2N2O3·2HCl
Molecular Weight
541.46
MDL Number
MFCD01703867
PubChem ID
122125
Melting Point
179 - 181 °C (dec.)
Appearance
White or off-white crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-[Bis(4-fluorophenyl)methyl]-4-(2,3,4-trimethoxybenzyl)piperazinedihydrochloride
CAS Number
101477-54-7
Purity
≥ 98.5% (Assay on dry basis)
Molecular Formula
C27H30F2N2O3·2HCl
Molecular Weight
541.46
MDL Number
MFCD01703867
PubChem ID
122125
Melting Point
179 - 181 °C (dec.)
Appearance
White or off-white crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Lomerizine dihydrochloride is widely utilized in research focused on:

  • Neurology: This compound is primarily used in studies related to migraine treatment, offering potential relief for patients by targeting specific pathways involved in headache mechanisms.
  • Pharmaceutical Development: It plays a crucial role in the formulation of new medications, particularly those aimed at vascular health, due to its ability to influence blood flow and circulation.
  • Cardiovascular Research: Researchers explore its effects on vascular smooth muscle, making it relevant in studies aimed at understanding and treating hypertension and other cardiovascular diseases.
  • Drug Interactions: Lomerizine dihydrochloride is studied for its interactions with other medications, helping to ensure patient safety and efficacy in multi-drug therapies.
  • Clinical Trials: It is often included in clinical trials to evaluate its effectiveness and safety, providing valuable data that can lead to new therapeutic options for patients suffering from chronic pain conditions.

Citations